Literature DB >> 6782507

Naloxone and focal epilepsy: a study with depth electrodes.

J Montplaisir, J M Saint-Hilaire, J T Walsh, M Laverdière, G Bouvier.   

Abstract

Intravenous injections of naloxone (0.8 to 2.4 mg) were given to patients with focal epilepsy who had had electrodes implanted in cortical and subcortical structures. There were no changes in interictal spike activity, responses to electrical stimulation, of frequency of spontaneous seizures. These data do not support the hypothesis that opiate peptides are involved in human focal epilepsy.

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Year:  1981        PMID: 6782507     DOI: 10.1212/wnl.31.3.350

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  1 in total

1.  Lack of clinical-EEG effects of naloxone injection on infantile spasms.

Authors:  A Nalin; F Petraglia; A R Genazzani; G Frigieri; F Facchinetti
Journal:  Childs Nerv Syst       Date:  1988-12       Impact factor: 1.475

  1 in total

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