Literature DB >> 6781001

Amphetamine stereotypies and polyribosomal disaggregation in rats: effects of adrenergic and serotonergic blocking agents.

M M Widelitz, C P Hable.   

Abstract

To find the specific chemical moiety responsible for the disaggregation of polyribosomes after induction of aberrant behavior by d-amphetamine, specific amine blockers and reserpine were utilized. It appears that dopamine is responsible for both the disaggregation of polyribosomes and stereotypic behavior while the roles of serotonin and norepinephrine are not significant in this system.

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Year:  1980        PMID： 6781001     DOI： 10.1007/BF00433815

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  6 in total

1.  Dissociation of rat brain polyribosomes in vivo by amphetamines.

Authors:  M M Widelitz; M R Coryell; H Widelitz; M G Avadhani
Journal:  Brain Res       Date:  1975-12-12       Impact factor: 3.252

2.  Effects of amphetamine administration in vivo on in vitro protein synthesizing system from rat brain.

Authors:  M M Widelitz; M R Coryell; H Widelitz; N G Avadhani
Journal:  J Neurochem       Date:  1976-08       Impact factor: 5.372

3.  Inhibition of cell-free protein synthesis initiation by amphetamine: association with reduction in tRNA aminoacylation.

Authors:  T S Nowak; H N Munro
Journal:  Biochem Biophys Res Commun       Date:  1977-08-22       Impact factor: 3.575

4.  The relative role of dopamine and norepinephrine receptor blockade in the action of antipsychotic drugs: metoclopramide, thiethylperazine, and molindone as pharmacological tools.

Authors:  S E Robinson; S Berney; R Mishra; F Sulser
Journal:  Psychopharmacology (Berl)       Date:  1979-08-08       Impact factor: 4.530

5.  Mechanism of D-amphetamine inhibition of protein synthesis.

Authors:  B S Baliga; J Zähringer; M Trachtenberg; M A Moskowitz; H N Munro
Journal:  Biochim Biophys Acta       Date:  1976-08-18

6.  Amphetamine-haloperidol interactions in rat striatum: failure to correlate behavioral effects with dopaminergic and cholinergic dynamics.

Authors:  R Kuczenski; D Schmidt; N Leith
Journal:  Brain Res       Date:  1977-04-22       Impact factor: 3.252
  6 in total

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