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Literature DB >> 6779715

Hypothalamic-pituitary-gonadotropic function in girls with premature thelarche.

A M Pasquino, F Piccolo, A Scalamandre, M Malvaso, R Ortolani, B Boscherini.

Abstract

Hypothalamic-pituitary-gonadotropic activity was investigated in 9 girls with premature thelarche, and compared with that in 9 healthy girls and 6 girls with true precocious puberty. The gonadotropin stimulation test with luteinising hormone-releasing hormone was used. Girls with premature thelarche showed luteinising hormone response resembling that of normal girls, and follicle-stimulating hormone (FSH) response quite similar to that of girls with precocious puberty. This suggests that in premature thelarche there is a partial activation of the diencephalic-hypophyseal-gonadal axis, which affects FSH only. Premature thelarche therefore, should be considered as one of the disorders due to altered sensitivity of the hypothalamic receptors which regulate sex maturation.

Entities: Disease Species

Mesh：

Substances：

Year: 1980 PMID： 6779715 PMCID： PMC1627206 DOI： 10.1136/adc.55.12.941

Source DB: PubMed Journal: Arch Dis Child ISSN： 0003-9888 Impact factor: 3.791

15 in total

Review 1. Sexual precocity.

Authors: J R Bierich
Journal: Clin Endocrinol Metab Date: 1975-03

2. Premature thelarche.

Authors: A Altchek
Journal: Pediatr Clin North Am Date: 1972-08 Impact factor: 3.278

3. Cervical and vaginal cytology in the child and adolescent.

Authors: R H Kaufman; L J Leeds
Journal: Pediatr Clin North Am Date: 1972-08 Impact factor: 3.278

4. Variations in pattern of pubertal changes in girls.

Authors: W A Marshall; J M Tanner
Journal: Arch Dis Child Date: 1969-06 Impact factor: 3.791

5. Radioimmunoassayable serum LH and FSH in girls with sexual precocity, premature thelarche and adrenarche.

Authors: F M Kenny; A R Midgley; R B Jaffe; L Y Garces; A Vazquez; F H Taylor
Journal: J Clin Endocrinol Metab Date: 1969-09 Impact factor: 5.958

6. Responsivity of pituitary gonadotropes to luteinizing hormone-releasing factor in idiopathic precocious puberty, precocious thelarche, precocious adrenarche, and in patients treated with medroxyprogesterone acetate.

Authors: E O Reiter; S L Kaplan; F A Conte; M M Grumbach
Journal: Pediatr Res Date: 1975-02 Impact factor: 3.756

7. Radioimmunoassay: a method for human chorionic gonadotropin and human luteinizing hormone.

Authors: A R Midgley
Journal: Endocrinology Date: 1966-07 Impact factor: 4.736

8. Urocytograms in normal children and various abnormal conditions.

Authors: C Preeyasombat; F M Kenny
Journal: Pediatrics Date: 1966-09 Impact factor: 7.124

9. Radioimmunoassay for human follicle-stimulating hormone.

Authors: A R Midgley
Journal: J Clin Endocrinol Metab Date: 1967-02 Impact factor: 5.958

10. Hormonal changes in puberty. IV. Plasma estradiol, LH, and FSH in prepubertal children, pubertal females, and in precocious puberty, premature thelarche, hypogonadism, and in a child with a feminizing ovarian tumor.

Authors: M R Jenner; R P Kelch; S L Kaplan; M M Grümbach
Journal: J Clin Endocrinol Metab Date: 1972-03 Impact factor: 5.958

12 in total

1. Clinical and hormonal studies in precocious puberty.

Authors: S Khandekar; R J Dash
Journal: Indian J Pediatr Date: 1990 May-Jun Impact factor: 1.967

2. Studies of gonadotrophin pulsatility and pelvic ultrasound examinations distinguish between isolated premature thelarche and central precocious puberty.

Authors: R Stanhope; N A Abdulwahid; J Adams; C G Brook
Journal: Eur J Pediatr Date: 1986-08 Impact factor: 3.183

Review 3. Precocious puberty.

Authors: P Colaco
Journal: Indian J Pediatr Date: 1997 Mar-Apr Impact factor: 1.967

Hypothalamic-pituitary-gonadotropic function in girls with premature thelarche.

Review 1. Sexual precocity.

2. Premature thelarche.

3. Cervical and vaginal cytology in the child and adolescent.

4. Variations in pattern of pubertal changes in girls.

5. Radioimmunoassayable serum LH and FSH in girls with sexual precocity, premature thelarche and adrenarche.

6. Responsivity of pituitary gonadotropes to luteinizing hormone-releasing factor in idiopathic precocious puberty, precocious thelarche, precocious adrenarche, and in patients treated with medroxyprogesterone acetate.

7. Radioimmunoassay: a method for human chorionic gonadotropin and human luteinizing hormone.

8. Urocytograms in normal children and various abnormal conditions.

9. Radioimmunoassay for human follicle-stimulating hormone.

10. Hormonal changes in puberty. IV. Plasma estradiol, LH, and FSH in prepubertal children, pubertal females, and in precocious puberty, premature thelarche, hypogonadism, and in a child with a feminizing ovarian tumor.

1. Clinical and hormonal studies in precocious puberty.

2. Studies of gonadotrophin pulsatility and pelvic ultrasound examinations distinguish between isolated premature thelarche and central precocious puberty.

Review 3. Precocious puberty.

4. Premature thelarche: a follow up study of 40 girls. Natural history and endocrine findings.

5. Massive breast enlargement in an infant girl with central nervous system dysfunction.

6. Pulsatile secretion of luteinizing hormone and sleep-related gonadotropin rhythms in girls with premature thelarche.

7. Pelvic ultrasonography: early differentiation between isolated premature thelarche and central precocious puberty.

8. Prognostic signs in the evolution of premature thelarche by discriminant analysis.

9. Serum nesfatin-1 and leptin levels in non-obese girls with premature thelarche.

10. Is premature thelarche in the first two years of life transient?