Literature DB >> 6778920

IGA in human bile and liver.

H Nagura, P D Smith, P K Nakane, W R Brown.   

Abstract

Hepatic bile IgA from 6 patients was measured by radioimmunoassay and characterized immunochemically. The concentration of IgA was 0.14 to 0.88 mg/ml. IgA associated with secretory component (SC) as well as unassociated with SC was demonstrated in all 6 samples; The proportion associated with SC (secretory IgA) was 72% to 95%. IgA and SC were localized immunocytochemically in liver and bile duct tissues by the peroxidase-labeled antibody method. Evidence favoring endocytic, SC-mediated transfer of IgA by intrahepatic and extrahepatic biliary epithelium, but not by hepatocytes, was found.

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Year:  1981        PMID： 6778920

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  44 in total

Review 1.  Defense system in the biliary tract against bacterial infection.

Authors:  J Y Sung; J W Costerton; E A Shaffer
Journal:  Dig Dis Sci       Date:  1992-05       Impact factor: 3.199

Review 2.  The immunopathology of human biliary cell epithelium.

Authors:  Ya-Hui Chuang; Ruth Y Lan; M Eric Gershwin
Journal:  Semin Immunopathol       Date:  2009-06-17       Impact factor: 9.623

3.  Expression and distribution of immunoglobulin G in the normal liver, hepatocarcinoma and postpartial hepatectomy liver.

Authors:  Yu Lei; Tao Huang; Meng Su; Jin Luo; Christine Korteweg; Jing Li; Zhengshan Chen; Yamei Qiu; Xingmu Liu; Meiling Yan; Yun Wang; Jiang Gu
Journal:  Lab Invest       Date:  2014-09-29       Impact factor: 5.662

4.  Hepatic vascular endothelial cells heterogenously express surface antigens associated with monocytes, macrophages and T lymphocytes.

Authors:  H Nagura; T Koshikawa; Y Fukuda; J Asai
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

5.  Secretory component and immunoglobulins in the intrahepatic biliary tree and peribiliary gland in normal livers and hepatolithiasis.

Authors:  H Sugiura; Y Nakanuma
Journal:  Gastroenterol Jpn       Date:  1989-06

6.  [Alcohol and IgA in the kidney].

Authors:  H Köhler
Journal:  Klin Wochenschr       Date:  1985-09-16

7.  S100 protein positive dendritic cells in primary biliary cirrhosis and other chronic inflammatory liver diseases. Relevance to pathogenesis?

Authors:  A J Demetris; C Sever; S Kakizoe; S Oguma; T E Starzl; R Jaffe
Journal:  Am J Pathol       Date:  1989-04       Impact factor: 4.307

8.  Gall bladder: the predominant source of bile IgA in man?

Authors:  D A Vuitton; E Seilles; P Claude; P Sava; D L Delacroix
Journal:  Clin Exp Immunol       Date:  1985-10       Impact factor: 4.330

9.  IgA- and secretory IgA-opsonized S. aureus induce a respiratory burst and phagocytosis by polymorphonuclear leucocytes.

Authors:  A Gorter; P S Hiemstra; P C Leijh; M E van der Sluys; M T van den Barselaar; L A van Es; M R Daha
Journal:  Immunology       Date:  1987-07       Impact factor: 7.397

10.  The polymeric immunoglobulin receptor (secretory component) mediates transport of immune complexes across epithelial cells: a local defense function for IgA.

Authors:  C S Kaetzel; J K Robinson; K R Chintalacharuvu; J P Vaerman; M E Lamm
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-01       Impact factor: 11.205
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