Literature DB >> 67783

The modulation of histamine release by alpha-adrenoceptors: evidences in murine neoplastic mast cells.

F Moroni, R Fantozzi, E Masini, P F Mannaioni.   

Abstract

Murine neoplastic mast cells which have been loaded with exogenous labelled histamine, released 14C-histamine when exposed to increasing concentrations of phenylephrine and noradrenaline. Adrenaline was only slightly effective, while isoprenaline and dibutyryl-cyclic-AMP were fully inactive. The release of histamine evoked by alpha-adrenergic agonists was antagonized by phentolamine, and left unchanged by practolol and cocaine. It is concluded that alpha-adrenoceptors may be valuable in evoking histamine release by murine neoplastic mast cells.

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Year:  1977        PMID： 67783     DOI： 10.1007/BF01964881

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  19 in total

1.  The uptake of amino acids and the synthesis of amines by neoplastic mast cells in culture.

Authors:  M DAY; J P GREEN
Journal:  J Physiol       Date:  1962-11       Impact factor: 5.182

2.  Effects of catecholamines on rat mesentery mast cells.

Authors:  M P De Oliveira; A M Rothschild
Journal:  Nature       Date:  1968-04-27       Impact factor: 49.962

3.  Cyclic AMP content and histamine release in rat mast cells.

Authors:  A R Johnson; N C Moran; S E Mayer
Journal:  J Immunol       Date:  1974-02       Impact factor: 5.422

4.  Immunologic release of chemical mediators from human nasal polyps.

Authors:  M Kaliner; S I Wasserman; K F Austen
Journal:  N Engl J Med       Date:  1973-08-09       Impact factor: 91.245

5.  Sequential analysis of the allergic response: cyclic AMP, calcium and histamine.

Authors:  L M Lichtenstein
Journal:  Int Arch Allergy Appl Immunol       Date:  1975

6.  A possible role for cyclic AMP in the regulation of histamine secretion and the action of cromoglycate.

Authors:  J C Foreman; J L Mongar; B D Gomperts; L G Garland
Journal:  Biochem Pharmacol       Date:  1975-02-15       Impact factor: 5.858

Review 7.  Current concepts on the secretory function of mast cells.

Authors:  A Goth; A R Johnson
Journal:  Life Sci       Date:  1975-04-15       Impact factor: 5.037

8.  Inhibition of the release of histamine from rat mast cells: the effect of cold and adrenergic drugs on release of histamine by compound 48-80 and antigen.

Authors:  A R Johnson; N C Moran
Journal:  J Pharmacol Exp Ther       Date:  1970-12       Impact factor: 4.030

9.  Studies on the 14C-histamine release induced by histamine in mouse neoplastic mast cells.

Authors:  F Moroni; R Fantozzi; E Masini; P F Mannaioni
Journal:  Agents Actions       Date:  1975-12

10.  Studies on the 14C-histamine release induced by noradrenaline in mouse neoplastic mast cells.

Authors:  P F Mannaioni; F Moroni; R Fantozzi; E Masini
Journal:  Agents Actions       Date:  1975-12
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  6 in total

Review 1.  Modulation of the spontaneous histamine release by adrenergic and cholinergic drugs.

Authors:  R Fantozzi; F Moroni; E Masini; P Blandina; P F Mannaioni
Journal:  Agents Actions       Date:  1978-06

Review 2.  Modulation of immune cell function by α(1)-adrenergic receptor activation.

Authors:  Laurel A Grisanti; Dianne M Perez; James E Porter
Journal:  Curr Top Membr       Date:  2011       Impact factor: 3.049

3.  Correlation between cholinergic histamine release and quinuclidinyl-benzilate ([3H]-QNB) binding in mast cell membranes.

Authors:  E Masini; P Blandina; R Fantozzi; S Brunelleschi; P F Mannaioni
Journal:  Agents Actions       Date:  1981-04

4.  Inhibition of methoxamine-induced bronchoconstriction by ipratropium bromide and disodium cromoglycate in asthmatic subjects.

Authors:  J Black; K Vincenc; C Salome
Journal:  Br J Clin Pharmacol       Date:  1985-07       Impact factor: 4.335

5.  Can the adrenergic system be implicated in the pathophysiology of bladder pain syndrome/interstitial cystitis? A clinical and experimental study.

Authors:  Ana Charrua; Rui Pinto; Anna Taylor; André Canelas; Alfredo Ribeiro-da-Silva; Célia D Cruz; Lori Ann Birder; Francisco Cruz
Journal:  Neurourol Urodyn       Date:  2013-12-24       Impact factor: 2.696

6.  α 1-Adrenergic Receptor Blockade by Prazosin Synergistically Stabilizes Rat Peritoneal Mast Cells.

Authors:  Nozomu Abe; Hiroaki Toyama; Yutaka Ejima; Kazutomo Saito; Tsutomu Tamada; Masanori Yamauchi; Itsuro Kazama
Journal:  Biomed Res Int       Date:  2020-05-12       Impact factor: 3.411
  6 in total

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