Literature DB >> 6778280

Waldenström's macroglobulinemia and autoimmune disease in a family.

W A Blattner, J E Garber, D L Mann, E A McKeen, R Henson, D B McGuire, W B Fisher, A W Bauman, L R Goldin, J F Fraumeni.   

Abstract

We diagnosed Waldenström's macroglobulinemia in a father and three offspring. Clinical and subclinical autoimmune disorders occurred excessively in the family. The HLA haplotype A2, B8, DRw3 was detected in all patients with Waldenström's macroglobulinemia and all but one family member with autoimmune manifestations. A lod score [log odds] of 4.86 favors linkage to the HLA complex of a gene predisposing to lymphoproliferative and autoimmune disorders. Associated with this HLA haplotype were the B-cell alloantigens Ia-172 and 350, previously reported in patients with the lymphoma-prone sicca syndrome.

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Year:  1980        PMID： 6778280     DOI： 10.7326/0003-4819-93-6-830

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN： 0003-4819            Impact factor:   25.391


  5 in total

1.  Chronic immune stimulation and subsequent Waldenström macroglobulinemia.

Authors:  Jill Koshiol; Gloria Gridley; Eric A Engels; Mary L McMaster; Ola Landgren
Journal:  Arch Intern Med       Date:  2008-09-22

2.  Differential characteristics of Waldenström macroglobulinemia according to patterns of familial aggregation.

Authors:  Regan H Royer; Jill Koshiol; Therese R Giambarresi; Linda G Vasquez; Ruth M Pfeiffer; Mary L McMaster
Journal:  Blood       Date:  2010-03-22       Impact factor: 22.113

3.  Risk of lymphoproliferative disorders among first-degree relatives of lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia patients: a population-based study in Sweden.

Authors:  Sigurdur Y Kristinsson; Magnus Björkholm; Lynn R Goldin; Mary L McMaster; Ingemar Turesson; Ola Landgren
Journal:  Blood       Date:  2008-08-13       Impact factor: 22.113

Review 4.  [Gluten-sensitive enteropathy--in the light of new clinical and pathogenetic aspects].

Authors:  F Kluge; H K Koch; E Köttgen; W Gerok
Journal:  Klin Wochenschr       Date:  1983-07-15

Review 5.  Waldenström's macroglobulinemia.

Authors:  K R Desikan; M V Dhodapkar; B Barlogie
Journal:  Curr Treat Options Oncol       Date:  2000-06
  5 in total

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