Literature DB >> 6776201

The isolation of immune complexes containing IgM rheumatoid factor and recovery of IgG rheumatoid factor from the complexes.

V E Jones, P J Cowley, C Allen, C J Elson.   

Abstract

IgG with rheumatoid factor activity has been recovered from immune complexes containing IgM rheumatoid factor. This was done by passing serum from patients with rheumatoid arthritis through an immunoadsorbent column of the F(ab')2 fragment of rabbit anti-human mu chain. The recovered IgM was analysed by radioimmunoassays for IgM and IgG rheumatoid factors before and after sucrose density gradient centrifugation at neutral and acid pH. It is considered that the method may be generally applicable for the isolation of immune complexes containing IgM antibodies.

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Year:  1980        PMID: 6776201     DOI: 10.1016/0022-1759(80)90176-3

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN: 0022-1759            Impact factor:   2.303


  10 in total

1.  Electrophoretic transfer blotting analysis of immune complexes in rheumatoid arthritis.

Authors:  R D Inman; N C Hamilton; P B Redecha; D M Hochhauser
Journal:  Clin Exp Immunol       Date:  1986-01       Impact factor: 4.330

2.  Rheumatoid vasculitis.

Authors:  D G Scott; P A Bacon
Journal:  Clin Rheumatol       Date:  1983-12       Impact factor: 2.980

3.  A new assay for IgG rheumatoid factor activity and its use to analyse rheumatoid factor reactivity with human IgG isotypes.

Authors:  C J Elson; S D Carter; D G Scott; P A Bacon; J Lowe
Journal:  Rheumatol Int       Date:  1985       Impact factor: 2.631

4.  Complement activating properties of complexes containing rheumatoid factor in synovial fluids and sera from patients with rheumatoid arthritis.

Authors:  C J Elson; S D Carter; B J Cottrell; D G Scott; P A Bacon; T B Wallington
Journal:  Clin Exp Immunol       Date:  1985-02       Impact factor: 4.330

5.  Synovial synthesis of rheumatoid factors and immune complex constituents in early arthritis.

Authors:  V Jones; P C Taylor; R K Jacoby; T B Wallington
Journal:  Ann Rheum Dis       Date:  1984-04       Impact factor: 19.103

6.  Detection and partial characterization of immune complexes in patients with rheumatoid arthritis plus Sjogren's syndrome and with Sjogren's syndrome alone.

Authors:  S Yoshinoya; S McDuffy; D Alarcon-Segovia; R M Pope
Journal:  Clin Exp Immunol       Date:  1982-05       Impact factor: 4.330

7.  Precipitation of 19S IgM rheumatoid factor-IgG circulating immune complexes in patients with juvenile arthritis by polyethylene glycol and separation by immobilized protein A.

Authors:  T L Moore; R W Dorner; P W Sheridan; J Zuckner
Journal:  Clin Exp Immunol       Date:  1984-05       Impact factor: 4.330

8.  Complement-activating rheumatoid-factor-containing complexes in patients with rheumatoid vasculitis.

Authors:  C J Elson; D G Scott; D R Blake; P A Bacon; P D Holt
Journal:  Ann Rheum Dis       Date:  1983-04       Impact factor: 19.103

9.  Mononuclear phagocytes in rheumatoid arthritis: Fc-receptor expression by peripheral blood monocytes.

Authors:  S D Carter; J T Bourne; C J Elson; C W Hutton; R Czudek; P A Dieppe
Journal:  Ann Rheum Dis       Date:  1984-06       Impact factor: 19.103

10.  Immune complexes in early arthritis. II. Immune complex constituents are synthesized in the synovium before rheumatoid factors.

Authors:  V E Jones; R K Jacoby; P J Cowley; C Warren
Journal:  Clin Exp Immunol       Date:  1982-07       Impact factor: 4.330

  10 in total

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