| Literature DB >> 6776133 |
V A Raisys, P N Friel, P R Graaff, K E Opheim, A J Wilensky.
Abstract
A one-step method for extraction of diazepam, nordiazepam, and internal standard into toluene is followed by chromatographic separation and detection with either dual-wave-length high-performance liquid chromatography or electron-capture gas-liquid chromatography. Agreement between the two methods was excellent for diazepam (r = 0.99, n = 38) and good for nordiazepam (r = 0.96, n = 79) over a concentration range that included subtherapeutic, therapeutic, and toxic plasma levels.Entities:
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Year: 1980 PMID： 6776133 DOI： 10.1016/s0378-4347(00)81586-8
Source DB: PubMed Journal: J Chromatogr