Literature DB >> 6774883

Histopathological modifications following immunotherapy with P 40 in rats bearing DMBA-induced mammary carcinoma.

K H Hollmann, J M Verley.   

Abstract

Female Sprague-Dawley rats bearing primarily-induced mammary carcinomas were treated with a new immunostimulating agent (P 40). The histopathological modifications encountered in tumors, lymph nodes, liver and spleen are described. Intratumoral injections provoke a more widespread response of the RES, and particularly a more intense reaction in the draining lymph nodes, than systemic treatment.

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Year:  1980        PMID： 6774883     DOI： 10.1007/bf01976136

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  13 in total

1.  Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression.

Authors:  C HUGGINS; L C GRAND; F P BRILLANTES
Journal:  Nature       Date:  1961-01-21       Impact factor: 49.962

2.  Histopathology of tumor regression after intralesional injection of Mycobacterium bovis. I. Tumor growth and metastasis.

Authors:  M G Hanna; B Zbar; H J Rapp
Journal:  J Natl Cancer Inst       Date:  1972-05       Impact factor: 13.506

3.  Rejection of tumors and metastases in Fischer 344 rats following intratumor administration of killed Corynebacterium parvum.

Authors:  V V Likhite
Journal:  Int J Cancer       Date:  1974-11-15       Impact factor: 7.396

4.  Comparison of the inhibition of tumor growth following local or systemic administration of Corynebacterium parvum or other immunostimulating agents with or without cyclophosphamide.

Authors:  B Fisher; M Gebhardt; J Linta; E Saffer
Journal:  Cancer Res       Date:  1978-09       Impact factor: 12.701

5.  Corynebacterium parvum as a therapeutic antitumor agent in mice. II. Local injection.

Authors:  M T Scott
Journal:  J Natl Cancer Inst       Date:  1974-09       Impact factor: 13.506

6.  Influence of immunotherapeutic agents on the progression of spontaneously arising, metastasizing rat mammary adenocarcinomas of varying immunogenicities.

Authors:  J A Greager; R W Baldwin
Journal:  Cancer Res       Date:  1978-01       Impact factor: 12.701

7.  Immunotherapy of an established rat mammary adenocarcinoma (13762A) with intratumor injection of Corynebacterium parvum.

Authors:  J W Kreider; G L Bartlett; D M Purnell; S Webb
Journal:  Cancer Res       Date:  1978-03       Impact factor: 12.701

8.  Antitumor activity of killed Corynebacterium parvum suspensions in a murine mammary adenocarcinoma CaD2) system.

Authors:  D M Purnell; J R Otterstrom; G L Bartlett; J W Kreider
Journal:  J Natl Cancer Inst       Date:  1976-06       Impact factor: 13.506

9.  Experimental cancer immunotherapy: comparison of tumor rejection if F344 rats given live Mycobacterium bovis (Strain BCG) and killed Corynebacterium parvum.

Authors:  V V Likhite
Journal:  J Natl Cancer Inst       Date:  1976-05       Impact factor: 13.506

10.  Effect of local injection of Corynebacterium parvum on the growth of a murine fibrosarcoma.

Authors:  M F Woodruff; N Dunbar
Journal:  Br J Cancer       Date:  1975-07       Impact factor: 7.640
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