Literature DB >> 6774373

Heroin, but not levorphanol, produces explosive motor behavior in naloxone-treated rats.

R Blair, H Cytryniak, P Shizgal, Z Amit.   

Abstract

Intraventricular infusions of heroin (an opiate) or levorphanol (an opioid) in rats produced rigidity but not explosive motor behavior (EMB). When preceded by an IP injection of naloxone, infusions of heroin but not levorphanol produced EMB. The results suggest that naloxone-antagonized effects of opiates mask EMB and that certain opioids do not induce EMB.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6774373     DOI： 10.1007/bf00433102

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  5 in total

1.  Opiate effects after adrenocorticotropin or beta-endorphin injection in the periaqueductal gray matter of rats.

Authors:  Y F Jacquet
Journal:  Science       Date:  1978-09-15       Impact factor: 47.728

2.  Naloxone's antagonism of rigidity but not explosive motor behavior: possible evidence for two types of mechanisms underlying the actions of opiates and opioids.

Authors:  R Blair; H Cytryniak; P Shizgal; Z Amit
Journal:  Behav Biol       Date:  1978-09

3.  Paradoxical effects after microinjection of morphine in the periaqueductal gray matter in the rat.

Authors:  Y F Jacquet; A Lajtha
Journal:  Science       Date:  1974-09-20       Impact factor: 47.728

4.  Explosive motor behavior, rigidity and periaqueductal gray lesions.

Authors:  R Blair; J Liran; H Cytryniak; P Shizgal; Z Amit
Journal:  Neuropharmacology       Date:  1978-03       Impact factor: 5.250

5.  Stereospecific and nonstereospecific effects of (+)- and (-)-morphine: evidence for a new class of receptors?

Authors:  Y F Jacquet; W A Klee; K C Rice; I Iijima; J Minamikawa
Journal:  Science       Date:  1977-11-25       Impact factor: 47.728
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.