Literature DB >> 6774

Chlorpromazine metabolism VIII: blood levels of chlorpromazine and its sulfoxide in schizophrenic patients.

P N Kaul, L R Whitfield, M L Clark.   

Abstract

A procedure was standardized for extracting chloropromazine and its sulfoxide from the blood and for applying a recently developed fluorometric assay method to determine blood levels of these two compounds in schizophrenic patients receiving chlorpromazine therapy. The described methodology opens avenues for performing bioavailability and generic equivalence studies in humans.

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Year:  1976        PMID: 6774     DOI: 10.1002/jps.2600650516

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  1 in total

1.  Chlorpromazine metabolism. IX. Pharmacokinetics of chlorpromazine following oral administration in man.

Authors:  L R Whitfield; P N Kaul; M L Clark
Journal:  J Pharmacokinet Biopharm       Date:  1978-06
  1 in total

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