Literature DB >> 6773144

Gap junction development is correlated with insulin content in the pancreatic B cell.

P Meda, P Halban, A Perrelet, A E Renold, L Orci.   

Abstract

The development of gap junctions between insulin-containing B cells was quantitatively analyzed in islets of Langerhans isolated from rats treated with the sulfonylurea glibenclamid for 1, 2, or 7 days. Glibenclamid treatment was associated with a marked depletion of the insulin content of B cells and with an increase in the number and size of gap junctions between these cells. A significance correlation was found between these two events.

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Year:  1980        PMID： 6773144     DOI： 10.1126/science.6773144

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  16 in total

1.  A method for mouse pancreatic islet isolation and intracellular cAMP determination.

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Journal:  J Vis Exp       Date:  2014-06-25       Impact factor: 1.355

Review 2.  Regulation of islet glucagon secretion: Beyond calcium.

Authors:  Jing W Hughes; Alessandro Ustione; Zeno Lavagnino; David W Piston
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Review 3.  Impact of islet architecture on β-cell heterogeneity, plasticity and function.

Authors:  Sara S Roscioni; Adriana Migliorini; Moritz Gegg; Heiko Lickert
Journal:  Nat Rev Endocrinol       Date:  2016-09-02       Impact factor: 43.330

4.  Connexins protect mouse pancreatic β cells against apoptosis.

Authors:  Philippe Klee; Florent Allagnat; Helena Pontes; Manon Cederroth; Anne Charollais; Dorothée Caille; Aurore Britan; Jacques-Antoine Haefliger; Paolo Meda
Journal:  J Clin Invest       Date:  2011-11-07       Impact factor: 14.808

Review 5.  Islet cell interactions with pancreatic B-cells.

Authors:  D Pipeleers
Journal:  Experientia       Date:  1984-10-15

6.  Hormonal modulation of gap junctions in rat ovarian follicles.

Authors:  R C Burghardt; E Anderson
Journal:  Cell Tissue Res       Date:  1981       Impact factor: 5.249

Review 7.  Physiologic relevance of heterogeneity in the pancreatic beta-cell population.

Authors:  D Pipeleers; R Kiekens; Z Ling; A Wilikens; F Schuit
Journal:  Diabetologia       Date:  1994-09       Impact factor: 10.122

8.  Electrical coupling between cells in islets of Langerhans from mouse.

Authors:  G T Eddlestone; A Gonçalves; J A Bangham; E Rojas
Journal:  J Membr Biol       Date:  1984       Impact factor: 1.843

9.  Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells.

Authors:  M Pérez-Armendariz; C Roy; D C Spray; M V Bennett
Journal:  Biophys J       Date:  1991-01       Impact factor: 4.033

10.  Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channels.

Authors:  E Charpantier; J Cancela; P Meda
Journal:  Diabetologia       Date:  2007-09-08       Impact factor: 10.122
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