Literature DB >> 6772354

Endocrine function and haemoglobinopathies: relation between the sickle cell gene and circulating plasma levels of testosterone, luteinising hormone (LH) and follicle stimulating hormone (FSH) in adult males.

O A Dada, E U Nduka.   

Abstract

Circulating plasma levels of testosterone, luteinising hormone and follicle stimulating hormone were determined in adult Nigerian males who have haemoglobin (Hb) genotypes HbAA, AS, AC, SC and SS. The levels of the three hormones were significantly lower in homozygous sickle cell disease (HbSS) compared to the other groups, whereas the levels of testosterone and luteinising hormone were significantly reduced in HbSC heterozygotes compared to HbAS heterozygotes only. These results are suggestive of an association of secondary hypogonadism with haemoglobin S disease.

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Year:  1980        PMID： 6772354     DOI： 10.1016/0009-8981(80)90469-6

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN： 0009-8981            Impact factor:   3.786


  12 in total

1.  Testosterone replacement in transgenic sickle cell mice controls priapic activity and upregulates PDE5 expression and eNOS activity in the penis.

Authors:  B Musicki; S Karakus; W Akakpo; F H Silva; J Liu; H Chen; B R Zirkin; A L Burnett
Journal:  Andrology       Date:  2017-11-16       Impact factor: 3.842

2.  Testicular dysfunction in men with sickle cell disease.

Authors:  D N Osegbe; O O Akinyanju
Journal:  Postgrad Med J       Date:  1987-02       Impact factor: 2.401

3.  Is testosterone deficiency a possible risk factor for priapism associated with sickle-cell disease?

Authors:  Belinda F Morrison; Uzoma A Anele; Marvin E Reid; Wendy A Madden; Zhaoyong Feng; Arthur L Burnett
Journal:  Int Urol Nephrol       Date:  2014-11-05       Impact factor: 2.370

4.  Hypogonadism in patients with sickle cell disease: central or peripheral?

Authors:  A Taddesse; I L Woldie; P Khana; P S Swerdlow; J-W Chu; J Abrams; A-B Abou-Samra
Journal:  Acta Haematol       Date:  2012-06-06       Impact factor: 2.195

5.  Serum testosterone level and semen quality in male patients with sickle cell disease in outpatient department of Chhattisgarh: a case-control study.

Authors:  Vinita Singh; Sabah Siddiqui; Nighat Hussain; Rachita Nanda; Amit Bugalia; Sarita Agrawal
Journal:  Int J Clin Exp Pathol       Date:  2022-06-15

Review 6.  Iron and copper in male reproduction: a double-edged sword.

Authors:  Eva Tvrda; Rohan Peer; Suresh C Sikka; Ashok Agarwal
Journal:  J Assist Reprod Genet       Date:  2014-09-23       Impact factor: 3.412

7.  Serum testosterone levels of HbSS (sickle cell disease) male subjects in Lagos, Nigeria.

Authors:  Emmanuel K Abudu; Sulaiman A Akanmu; Oyetunji O Soriyan; Akinsegun A Akinbami; Adewumi Adediran; Titilope A Adeyemo; Charles C Okany
Journal:  BMC Res Notes       Date:  2011-08-17

8.  Sickling cells, cyclic nucleotides, and protein kinases: the pathophysiology of urogenital disorders in sickle cell anemia.

Authors:  Mário Angelo Claudino; Kleber Yotsumoto Fertrin
Journal:  Anemia       Date:  2012-06-13

9.  Mechanism of testosterone deficiency in the transgenic sickle cell mouse.

Authors:  Biljana Musicki; Yuxi Zhang; Haolin Chen; Terry R Brown; Barry R Zirkin; Arthur L Burnett
Journal:  PLoS One       Date:  2015-05-29       Impact factor: 3.240

10.  Does blood transfusion affect pituitary gonadal axis and sperm parameters in young males with sickle cell disease?

Authors:  Ashraf T Soliman; Mohamed Yasin; Ahmed El-Awwa; Mohamed O Abdelrahman; Vincenzo De Sanctis
Journal:  Indian J Endocrinol Metab       Date:  2013-11
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