| Literature DB >> 6771892 |
M I Thabrew, E A Bababunmi, M R French.
Abstract
The metabolic fate of [14C] benzoic acid administered i.p. to marasmic-kwashiorkor rats has been investigated. Rats fed a normal diet with benzoic acid administered i.p. at 200 mg/kg, excreted the benzoic acid mainly as hippuric acid (99% of 24 h excretion), while marasmic-kwashiorkor rats excreted 62--85% as hippuric acid and 14--37% as the glucuronide conjugate. 2 weeks after repletion metabolism of benzoic acid by the marasmic-kwashiorkor rats on the stock diet had returned to normal; most of the benzoate was excreted as hippuric acid.Entities:
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Year: 1980 PMID： 6771892 DOI： 10.1016/0378-4274(80)90016-8
Source DB: PubMed Journal: Toxicol Lett ISSN： 0378-4274 Impact factor: 4.372