| Literature DB >> 6771778 |
M Ali, C G Gudbranson, J W McDonald.
Abstract
Alpha-tocopherol, an inhibitor of platelet aggregation, was evaluated for its effects on the synthesis of thromboxane and prostaglandins. A dose-dependent reduction in thromboxane B2 and prostaglandin D2 synthesis was observed with approximately 60% inhibition at 5.0 IU or alpha-tocopherol. Alpha-tocopherol produced a time-dependent, irreversible inhibition.Entities:
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Year: 1980 PMID: 6771778 DOI: 10.1016/0161-4630(80)90038-5
Source DB: PubMed Journal: Prostaglandins Med ISSN: 0161-4630