Literature DB >> 6770989

Emergence of immunoblastic sarcoma in Waldenstrom's macroglobulinemia.

S A Leonhard, A F Muhleman, P E Hurtubise, O J Martelo.   

Abstract

A case involving a 65-year-old man with Waldenstrom's macroglobulinemia (WMG) which transformed into immunoblastic sarcoma is presented. Surface IgM (kappa) was demonstrated on the plasmacytoid lymphocytes of the bone marrow at presentation as well as on the less differentiated cells of the immunoblastic sarcoma. Serum IgM levels fell at the time that immunoblastic transformation occurred. This case illustrates the fact that a fall in serum paraprotein may herald a malignant transformation of WMG.

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Year:  1980        PMID: 6770989     DOI: 10.1002/1097-0142(19800615)45:12<3102::aid-cncr2820451237>3.0.co;2-9

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  3 in total

1.  Conversion of an IGM secreting immunocytoma in a high grade malignant lymphoma of immunoblastic type.

Authors:  B Emmerich; M Pemsl; I Wüst; W E Berdel; S Lechner; E Thiel; A Georgii; W Gössner; J Rastetter
Journal:  Blut       Date:  1983-02

2.  Jh gene sequence analysis in a patient with Waldenström's macroglobulinaemia with subsequent development of immunoblastic lymphoma.

Authors:  H Kondo; N Yumoto; A Mikata; Y Date
Journal:  Clin Mol Pathol       Date:  1995-08

3.  Regulation of B cell lymphomagenesis by a malignant Qal+ inducer T cell clone.

Authors:  C L Reinisch; A P Sing; E R Bacon; R B Corley; R K Gershon
Journal:  J Exp Med       Date:  1984-03-01       Impact factor: 14.307

  3 in total

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