Literature DB >> 6770503

The longevity of antibody to Rickettsia tsutsugamushi in patients with confirmed scrub typhus.

J P Saunders, G W Brown, A Shirai, D L Huxsoll.   

Abstract

Serological surveillance for up to two years of 114 patients with laboratory confirmed scrub typhus showed that antibody to Rickettsia tsutsugamushi as demonstrated by the indirect fluorescent antibody test is short-lived. The mean reversion time from mean peak titre (1:499) was 48.9 weeks and the calculated annual reversion rate to a titre less than 1:50 was 61%. This can be used to estimate attack rates based on point prevalence of antibody. The relationship between antibody prevalence and attack rates observed by other workers was confirmed using this model. The possible uses of the finding and its implications in Malaysia are briefly discussed.

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Year:  1980        PMID: 6770503     DOI: 10.1016/0035-9203(80)90254-0

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  16 in total

1.  A case of Tsutsugamushi disease probably contracted in Africa.

Authors:  K Osuga; M Kimura; H Goto; K Shimada; T Suto
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-02       Impact factor: 3.267

Review 2.  Unresolved problems related to scrub typhus: a seriously neglected life-threatening disease.

Authors:  Daniel H Paris; Thomas R Shelite; Nicholas P Day; David H Walker
Journal:  Am J Trop Med Hyg       Date:  2013-08       Impact factor: 2.345

Review 3.  Laboratory diagnosis of rickettsioses: current approaches to diagnosis of old and new rickettsial diseases.

Authors:  B La Scola; D Raoult
Journal:  J Clin Microbiol       Date:  1997-11       Impact factor: 5.948

4.  Early diagnosis of scrub typhus with a rapid flow assay using recombinant major outer membrane protein antigen (r56) of Orientia tsutsugamushi.

Authors:  W M Ching; D Rowland; Z Zhang; A L Bourgeois; D Kelly; G A Dasch; P L Devine
Journal:  Clin Diagn Lab Immunol       Date:  2001-03

5.  Accuracy of AccessBio Immunoglobulin M and Total Antibody Rapid Immunochromatographic Assays for the Diagnosis of Acute Scrub Typhus Infection.

Authors:  Stuart D Blacksell; Kemajittra Jenjaroen; Rattanaphone Phetsouvanh; Vanaporn Wuthiekanun; Nicholas P J Day; Paul N Newton; Wei-Mei Ching
Journal:  Clin Vaccine Immunol       Date:  2009-12-16

6.  Accuracy of rapid IgM-based immunochromatographic and immunoblot assays for diagnosis of acute scrub typhus and murine typhus infections in Laos.

Authors:  Stuart D Blacksell; Kemajittra Jenjaroen; Rattanaphone Phetsouvanh; Ampai Tanganuchitcharnchai; Phonlavanh Phouminh; Simalee Phongmany; Nicholas P J Day; Paul N Newton
Journal:  Am J Trop Med Hyg       Date:  2010-08       Impact factor: 2.345

7.  Contrasting spatial distribution and risk factors for past infection with scrub typhus and murine typhus in Vientiane City, Lao PDR.

Authors:  Julie Vallée; Thaksinaporn Thaojaikong; Catrin E Moore; Rattanaphone Phetsouvanh; Allen L Richards; Marc Souris; Florence Fournet; Gérard Salem; Jean-Paul J Gonzalez; Paul N Newton
Journal:  PLoS Negl Trop Dis       Date:  2010-12-07

Review 8.  An Update on Host-Pathogen Interplay and Modulation of Immune Responses during Orientia tsutsugamushi Infection.

Authors:  Fabián E Díaz; Katia Abarca; Alexis M Kalergis
Journal:  Clin Microbiol Rev       Date:  2018-01-31       Impact factor: 26.132

9.  Expression and refolding of truncated recombinant major outer membrane protein antigen (r56) of Orientia tsutsugamushi and its use in enzyme-linked immunosorbent assays.

Authors:  W M Ching; H Wang; C Eamsila; D J Kelly; G A Dasch
Journal:  Clin Diagn Lab Immunol       Date:  1998-07

Review 10.  Approaches to vaccines against Orientia tsutsugamushi.

Authors:  Gustavo Valbuena; David H Walker
Journal:  Front Cell Infect Microbiol       Date:  2013-01-04       Impact factor: 5.293

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