| Literature DB >> 6770342 |
Abstract
Transepithelial urea outfluxes across toad gallbladder were determined before and after the addition of cycloheximide. The drug inhibits the movement of urea but has no effect on thiourea and antipyrine outfluxes. The inhibition of amide transport is time dependent as also shown in counterflow experiments. These results are consistent with the hypothesis that cycloheximide inhibits the synthesis of membrane proteic sites involved in urea mediated transport.Entities:
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Year: 1980 PMID: 6770342 DOI: 10.1007/bf00584432
Source DB: PubMed Journal: Pflugers Arch ISSN: 0031-6768 Impact factor: 3.657