Literature DB >> 6770339

Acid base status in unanesthetized, unrestrained guinea pigs.

A Bar-Ilan, J Marder.   

Abstract

Acid-base status of arterial blood was measured in chronically cannulated, unanesthetized, unrestrained guinea pigs. Normal values were: pH = 7.444 +/- 0.032; PaCO2 = 35.7 +/- 4.4; HCO3- = 24.4 +/- 2.8; BE = +0.4 +/- 2.1 (n = 69) and PaCO2 = 91.9 +/- 7.3 (n = 25) (Values are mean +/- S.D.). Induction of light anesthesia with thiopentone caused a respiratory depression (decrease in PaO2) accompanied by respiratory acidosis (increase in PaCO2 and decrease in pH) and a development of slight metabolic acidosis (decrease in base excess and standard bicarbonate). Acid base parameters of guinea pigs are compared to those obtained from rats under identical experimental conditions.

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Year:  1980        PMID： 6770339     DOI： 10.1007/bf00589520

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


  32 in total

1.  Innovar-Vet-induced pathologic changes in the guinea pig.

Authors:  W M Newton; P K Cusick; M R Raffe
Journal:  Lab Anim Sci       Date:  1975-10

2.  Intravenous injection and blood sampling using cannulated guinea pigs.

Authors:  R E Shrader; G J Everson
Journal:  Lab Anim Care       Date:  1968-04

3.  The use of Innovar-Vet as a surgical anesthetic for the guinea pig.

Authors:  W C Rubright; C B Thayer
Journal:  Lab Anim Care       Date:  1970-10

4.  A comparative study of the performance of five commercial blood-gas and pH electrode analysers.

Authors:  D W Hill; C Tilsley
Journal:  Br J Anaesth       Date:  1973-07       Impact factor: 9.166

5.  Arterial acid-base changes in unanaesthetized rats in acute hypoxia.

Authors:  L D Lewis; U Pontén; B K Siesjö
Journal:  Respir Physiol       Date:  1973-12

6.  Anesthesia in the guinea pig.

Authors:  R M Hoar
Journal:  Fed Proc       Date:  1969 Jul-Aug

7.  The effect of general anesthesia on the chemical composition of blood plasma of normal rabbits.

Authors:  L Z Bito; K E Eakins
Journal:  J Pharmacol Exp Ther       Date:  1969-10       Impact factor: 4.030

8.  Arterial blood gases in conscious rats exposed to hypoxia, hypercapnia, or both.

Authors:  W E Pepelko; G A Dixon
Journal:  J Appl Physiol       Date:  1975-04       Impact factor: 3.531

9.  The effects of pentobarbitone anaesthesia on the volume and composition of the extracellular fluid of dogs.

Authors:  D S Rampton; D J Ramsay
Journal:  J Physiol       Date:  1974-03       Impact factor: 5.182

10.  Influence of age and starvation on pO2, pCO2 and haematocrit values in the rat.

Authors:  J Mourek
Journal:  Physiol Bohemoslov       Date:  1976
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  5 in total

1.  Osteocalcin, but not deoxypyridinoline, increases in response to isoflurane-induced anaesthesia in young female guinea pigs.

Authors:  Negar Tabatabaei; Celia J Rodd; Richard Kremer; Hope A Weiler
Journal:  J Bone Miner Metab       Date:  2014-05-24       Impact factor: 2.626

2.  Lipoxygenase metabolites mediate increased airways responsiveness to histamine after acute platelet activating factor exposure in the guinea-pig.

Authors:  G P Anderson; M R Fennessy
Journal:  Agents Actions       Date:  1988-06

3.  The effect of ether, pentobarbitone sodium and fentanyl on blood gases, acid-base balance and hematological parameters in the rat.

Authors:  J Komarek
Journal:  Experientia       Date:  1984-05-15

4.  Renal and single-nephron function is comparable in thiobutabarbitone- and thiopentone-anaesthetised rats.

Authors:  D A Häberle; J M Davis; M Kawabata; C Metz; P Wapler; M Stachl
Journal:  Pflugers Arch       Date:  1993-08       Impact factor: 3.657

5.  Normative data for arterial blood gas and electrolytes in anesthetized rats.

Authors:  Rajam Krishna Subramanian; Anita Sidharthan; Delinda Maneksh; Latha Ramalingam; A Soosai Manickam; Praghalathan Kanthakumar; Sathya Subramani
Journal:  Indian J Pharmacol       Date:  2013 Jan-Feb       Impact factor: 1.200
  5 in total

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