Literature DB >> 6770076

Prediction of steady-state behavior of metabolite from dosing of parent drug.

E A Lane, R H Levy.   

Abstract

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Year:  1980        PMID： 6770076     DOI： 10.1002/jps.2600690541

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


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  9 in total

Review 1.  A review of metabolite kinetics.

Authors:  K S Pang
Journal:  J Pharmacokinet Biopharm       Date:  1985-12

2.  Metabolite pharmacokinetics: the area under the curve of metabolite and the fractional rate of metabolism of a drug after different routes of administration for renally and hepatically cleared drugs and metabolites.

Authors:  K S Pang
Journal:  J Pharmacokinet Biopharm       Date:  1981-08

3.  Metabolite to parent drug concentration ratio as a function of parent drug extraction ratio: cases of nonportal route of administration.

Authors:  E A Lane; R H Levy
Journal:  J Pharmacokinet Biopharm       Date:  1981-08

Review 4.  Rationalization and prediction of in vivo metabolite exposures: the role of metabolite kinetics, clearance predictions and in vitro parameters.

Authors:  Justin D Lutz; Yasushi Fujioka; Nina Isoherranen
Journal:  Expert Opin Drug Metab Toxicol       Date:  2010-09       Impact factor: 4.481

5.  The N-demethylation of imipramine correlates with the oxidation of S-mephenytoin (S/R-ratio). A population study.

Authors:  E Skjelbo; L F Gram; K Brøsen
Journal:  Br J Clin Pharmacol       Date:  1993-03       Impact factor: 4.335

6.  Mechanistic PBPK Modeling of Urine pH Effect on Renal and Systemic Disposition of Methamphetamine and Amphetamine.

Authors:  Weize Huang; Lindsay C Czuba; Nina Isoherranen
Journal:  J Pharmacol Exp Ther       Date:  2020-03-20       Impact factor: 4.030

7.  Differential kinetics of cinromide and two of its metabolites in epileptic patients.

Authors:  A J Wilensky; E A Lane; R H Levy; L M Ojemann; P N Friel
Journal:  Eur J Clin Pharmacol       Date:  1981       Impact factor: 2.953

8.  Pharmacokinetics and pharmacodynamic modeling of direct suppression effects of methylprednisolone on serum cortisol and blood histamine in human subjects.

Authors:  A N Kong; E A Ludwig; R L Slaughter; P M DiStefano; J DeMasi; E Middleton; W J Jusko
Journal:  Clin Pharmacol Ther       Date:  1989-12       Impact factor: 6.875

9.  Inhibition of epoxidation of carbamazepine by valproic acid in the isolated perfused rat liver.

Authors:  S L Chang; R H Levy
Journal:  J Pharmacokinet Biopharm       Date:  1985-10
  9 in total

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