Literature DB >> 6769907

A mutant Ebg enzyme that converts lactose into an inducer of the lac operon.

S J Rolseth, V A Fried, B G Hall.   

Abstract

Lactose is not itself an inducer of the lac operon, nor is it converted to an inducer by ebg+ beta-galactosidase of Escherichia coli. We report here the isolation of a mutant Ebg beta-galactosidase which is capable of converting lactose into an inducer of the lac operon.

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Year:  1980        PMID： 6769907      PMCID： PMC294136          DOI： 10.1128/jb.142.3.1036-1039.1980

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  12 in total

1.  Regulation of newly evolved enzymes. II. The ebg repressor.

Authors:  B G Gall; D L Hartl
Journal:  Genetics       Date:  1975-11       Impact factor: 4.562

2.  Methyl galactosidase activity: an alternative evolutionary destination for the ebgA0 gene.

Authors:  B G Hall
Journal:  J Bacteriol       Date:  1976-04       Impact factor: 3.490

3.  A quantitation of the factors which affect the hydrolase and transgalactosylase activities of beta-galactosidase (E. coli) on lactose.

Authors:  R E Huber; G Kurz; K Wallenfels
Journal:  Biochemistry       Date:  1976-05-04       Impact factor: 3.162

4.  A mutation allowing utilisation of lactose by Escherichia coli lacY mutants defective in lactose permease.

Authors:  A C Hobson
Journal:  Mol Gen Genet       Date:  1978-04-25

5.  Regulation of newly evolved enzymes. III Evolution of the ebg repressor during selection for enhanced lactase activity.

Authors:  B G Hall; N D Clarke
Journal:  Genetics       Date:  1977-02       Impact factor: 4.562

6.  lac Repressor-operator interaction. VI. The natural inducer of the lac operon.

Authors:  A Jobe; S Bourgeois
Journal:  J Mol Biol       Date:  1972-08-28       Impact factor: 5.469

7.  Transport systems for galactose and galactosides in Escherichia coli. II. Substrate and inducer specificities.

Authors:  B Rotman; A K Ganesan; R Guzman
Journal:  J Mol Biol       Date:  1968-09-14       Impact factor: 5.469

8.  Experimental evolution of a new enzymatic function. Kinetic analysis of the ancestral (ebg) and evolved (ebg) enzymes.

Authors:  B G Hall
Journal:  J Mol Biol       Date:  1976-10-15       Impact factor: 5.469

9.  Regulation of newly evolved enzymes. I. Selection of a novel lactase regulated by lactose in Escherichia coli.

Authors:  B G Hall; D L Hartl
Journal:  Genetics       Date:  1974-03       Impact factor: 4.562

10.  Lactose permeation via the arabinose transport system in Escherichia coli K-12.

Authors:  A Messer
Journal:  J Bacteriol       Date:  1974-10       Impact factor: 3.490
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  3 in total

1.  DNA sequence analysis of artificially evolved ebg enzyme and ebg repressor genes.

Authors:  B G Hall; P W Betts; J C Wootton
Journal:  Genetics       Date:  1989-12       Impact factor: 4.562

2.  Evolution of a regulated operon in the laboratory.

Authors:  B G Hall
Journal:  Genetics       Date:  1982 Jul-Aug       Impact factor: 4.562

3.  Transgalactosylation activity of ebg beta-galactosidase synthesizes allolactose from lactose.

Authors:  B G Hall
Journal:  J Bacteriol       Date:  1982-04       Impact factor: 3.490
  3 in total

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