| Literature DB >> 6769752 |
M Obata, Y Yamawaki-Kataoka, N Takahashi, T Kataoka, A Shimizu, Y Mano, J G Seidman, B M Peterlin, P Leder, T Honjo.
Abstract
Immunoglobulin gamma 1 heavy chain cDNA was cloned into an Escherichia coli plasmid pCR1 and its nucleotide sequence was determined. The hybrid plasmid contained approx. 900-bases-long gamma 1 chain cDNA sequence, including the complete sequence of the CH2 and CH3 domains and the 3' untranslated region, and partial sequence of the CH1 domain. The nucleotide sequence predicts an extra lysine at the carboxyl-terminus of the gamma 1 chain. Comparison of the nucleotide sequence of 3' untranslated regions of the immunoglobulin gamma 1 chain and kappa light chain showed a significant homology although lengths are quite divergent.Entities:
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Year: 1980 PMID： 6769752 DOI： 10.1016/0378-1119(80)90168-7
Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688