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Literature DB >> 6769702

Effect of cyproheptadine on the octopamine-induced responses in the mammalian central nervous system.

Abstract

Extracellular recordings have been made from rat thalamic neurones anaesthetized with urethane, 1.5--2 g/kg i.p. Iontophoretically applied octopamine excited certain thalamic neurones in the ventral basal complex while inhibiting others. Both effects were reversibly antagonized by iontophoretically applied cyproheptadine without affecting responses to noradrenaline and dopamine.

Entities: Chemical Species

Mesh：

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Year: 1980 PMID： 6769702 DOI： 10.1007/bf01965816

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

14 in total

1. An octopamine-sensitive adenylate cyclase in the central nervous system of Limulus polyphemus.

Authors: M M Atkinson; W S Herman; J R Sheppard
Journal: Comp Biochem Physiol C Comp Pharmacol Date: 1977

2. The first family (adrenaline, noradrenaline, dopamine, octopamine, tyramine, phenylethanolamine and phenylethylamine).

Authors: R J Walker; G A Kerkut
Journal: Comp Biochem Physiol C Date: 1978

3. Differential blockade of octopamine and dopamine receptors by analogues of clozapine and metoclopramide.

Authors: D F Dougan; D N Wade
Journal: Clin Exp Pharmacol Physiol Date: 1978 Jul-Aug Impact factor: 2.557

4. m-Octopamine, p-octopamine and phenylethanolamine in rat brain: a sensitive, specific assay and the effects of some drugs.

Authors: T J Danielson; A A Boulton; H A Robertson
Journal: J Neurochem Date: 1977-12 Impact factor: 5.372

5. Octopamine-sensitive adenylate cyclase in cockroach brain: effects of agonists, antagonists, and guanylyl nucleotides.

Authors: A J Harmar; A S Horn
Journal: Mol Pharmacol Date: 1977-05 Impact factor: 4.436

Effect of cyproheptadine on the octopamine-induced responses in the mammalian central nervous system.

1. An octopamine-sensitive adenylate cyclase in the central nervous system of Limulus polyphemus.

2. The first family (adrenaline, noradrenaline, dopamine, octopamine, tyramine, phenylethanolamine and phenylethylamine).

3. Differential blockade of octopamine and dopamine receptors by analogues of clozapine and metoclopramide.

4. m-Octopamine, p-octopamine and phenylethanolamine in rat brain: a sensitive, specific assay and the effects of some drugs.

5. Octopamine-sensitive adenylate cyclase in cockroach brain: effects of agonists, antagonists, and guanylyl nucleotides.

6. [Localization of glass microelectrode extremities in the central nervous system by pontamine electrophoresis].

7. Pharmacological studies on Helix neuron octopamine receptors.

8. Problems associated with iontophoretic studies in the caudate nucleus and substantia nigra.

9. Micromethods in neuropharmacology: an approach to the study of anesthetics.

10. Comparison of the actions of octopamine and catecholamines on single neurones of the rat cerebral cortex.

Review 1. Trace amine-associated receptor 1-Family archetype or iconoclast?

2. Multiple receptor types for octopamine in the locust.

3. Octopamine and locomotor activity of rats.

4. A modulatory octopaminergic neurone increases cyclic nucleotide levels in locust skeletal muscle.

Review 5. Emerging agents and regimens for AML.