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Literature DB >> 6769059

In vitro polymerization of glial fibrillary acidic (GFA) protein extracted from multiple sclerosis (MS) brain.

Abstract

Aqueous extracts of multiple sclerosis plaques were used for reaggregation studies of filamentous proteins. Filament formation as observed by electron microscopy was dependent on temperature, pH, and energy. The major protein component in the filaments had chemical and immunological properties of the glial fibrillary acidic protein.

Entities: Disease

Mesh：

Substances：

Year: 1980 PMID： 6769059 DOI： 10.1007/bf00964613

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

13 in total

1. The topographical distribution of S-100 and GFA proteins in the adult rat brain: an immunohistochemical study using horseradish peroxidase-labelled antibodies.

Authors: S K Ludwin; J C Kosek; L F Eng
Journal: J Comp Neurol Date: 1976-01-15 Impact factor: 3.215

2. Solubilization of neurofilaments from central nervous system myelinated nerve.

Authors: W A Day
Journal: J Ultrastruct Res Date: 1977-09

3. Measurement of glial fibrillary acidic protein by a two-site immunoradiometric assay.

Authors: L F Eng; Y L Lee; L E Miles
Journal: Anal Biochem Date: 1976-03 Impact factor: 3.365

4. Biochemical correlates of astrocytic proliferation in the mutant Staggerer mouse.

Authors: V Lee; S H Yen; M L Shelanski
Journal: Brain Res Date: 1977-06-10 Impact factor: 3.252

5. Contribution of immunohistochemistry to diagnostic problems of human cerebral tumors.

Authors: L F Eng; L J Rubinstein
Journal: J Histochem Cytochem Date: 1978-07 Impact factor: 2.479

6. Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence.

Authors: A Bignami; L F Eng; D Dahl; C T Uyeda
Journal: Brain Res Date: 1972-08-25 Impact factor: 3.252

7. Glial fibrillary acidic protein from normal human brain. Purification and properties.

Authors: D Dahl; A Bignami
Journal: Brain Res Date: 1973-07-27 Impact factor: 3.252

8. Immunological study of the glial fibrillary acidic protein.

Authors: C T Uyeda; L F Eng; A Bignami
Journal: Brain Res Date: 1972-02-11 Impact factor: 3.252

9. Ultrastructural localization of glial fibrillary acidic protein in mouse cerebellum by immunoperoxidase labeling.

Authors: M Schachner; E T Hedley-Whyte; D W Hsu; G Schoonmaker; A Bignami
Journal: J Cell Biol Date: 1977-10 Impact factor: 10.539

10. Isolation and characterization of glial filaments from human brain.

Authors: J E Goldman; H H Schaumburg; W T Norton
Journal: J Cell Biol Date: 1978-08 Impact factor: 10.539

9 in total

1. Cytoskeletal properties and endogenous degradation of glial fibrillary acidic protein and vimentin in cultured human glioma cells.

Authors: A Paetau; I Virtanen
Journal: Acta Neuropathol Date: 1986 Impact factor: 17.088

2. Choroid plexus tumors in infancy and childhood. Focal ependymal differentiation. An immunoperoxidase study.

Authors: A L Taratuto; H Molina; J Monges
Journal: Acta Neuropathol Date: 1983 Impact factor: 17.088

3. Calcium-mediated breakdown of glial filaments and neurofilaments in rat optic nerve and spinal cord.

Authors: W W Schlaepfer; U P Zimmerman
Journal: Neurochem Res Date: 1981-03 Impact factor: 3.996

4. Globular glial fibrillary acidic protein-reactive cytoplasmic inclusions in ependymoma: an immunoelectron-microscopic study.

Authors: J L Twiss; L J Anderson; D S Horoupian
Journal: Acta Neuropathol Date: 1993 Impact factor: 17.088

Review 9. Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO.

Authors: Vidya Narayanaswami; Kenneth Dahl; Vadim Bernard-Gauthier; Lee Josephson; Paul Cumming; Neil Vasdev
Journal: Mol Imaging Date: 2018 Jan-Dec Impact factor: 4.488