Literature DB >> 6768815

A human lymphocyte mitogen extracted from the extracellular slime layer of Pseudomonas aeruginosa.

M Papamichail, G Dimitracopoulos, G Tsokos, J Papavassiliou.   

Abstract

Slime glycolipoprotein of Pseudomonas aeruginosa has been found to exert a mitogenic effect on human peripheral blood and cord blood lymphocytes. The optimal concentration of glycolipoprotein was shown to be in the range of 100--200 micrograms/ml, and maximal incorporation of [14C]thymidine was seen on the fourth day of lymphocyte cultures.

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Year:  1980        PMID： 6768815     DOI： 10.1093/infdis/141.5.686

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  6 in total

1.  Biological effects of Pseudomonas aeruginosa exotoxin A: lymphoproliferation of T lymphocytes in athymic mice.

Authors:  P S Holt; M L Misfeldt
Journal:  Eur J Epidemiol       Date:  1988-03       Impact factor: 8.082

2.  Mitogenic effects of glycolipoprotein extract from Pseudomonas aeruginosa.

Authors:  A M Varey; A Cooke; G Dimitrocopoulos; M Papamichail
Journal:  Clin Exp Immunol       Date:  1984-05       Impact factor: 4.330

Review 3.  Cystic fibrosis. Infection and immunity to Pseudomonas.

Authors:  R U Sorensen; R L Waller; J D Klinger
Journal:  Clin Rev Allergy       Date:  1991 Spring-Summer

4.  Pseudomonas aeruginosa slime glycolipoprotein is a potent stimulant of tumor necrosis factor alpha gene expression and activation of transcription activators nuclear factor kappa B and activator protein 1 in human monocytes.

Authors:  George Lagoumintzis; Myrto Christofidou; George Dimitracopoulos; Fotini Paliogianni
Journal:  Infect Immun       Date:  2003-08       Impact factor: 3.441

5.  Comparative evaluation of mitogenicity and basement-membrane-degrading activity of Pseudomonas aeruginosa slime glycolipoprotein and alginate.

Authors:  E D Anastassiou; G Karakiulakis; E Missirlis; M E Maragoudakis; G Dimitracopoulos
Journal:  J Clin Microbiol       Date:  1989-03       Impact factor: 5.948

6.  In vitro response of human T cells to Pseudomonas aeruginosa.

Authors:  J M Porwoll; H M Gebel; G E Rodey; R B Markham
Journal:  Infect Immun       Date:  1983-05       Impact factor: 3.441
  6 in total

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