Literature DB >> 6768811

Enhanced chemotaxis to gentamicin-resistant strains of Pseudomonas aeruginosa.

H P Bassaris, P E Lianou, A S Dontas, N J Legakis, J T Papavassiliou.   

Abstract

The chemotactic response of human polymorphonuclear leukocytes (PMNLs) to gentamicin-sensitive and gentamicin-resistant strains of Pseudomonas aeruginosa was studied. Filtrates from the resistant strains markedly enhanced the chemotactic response of human PMNLs (leukotactic index [LI] = 40.4 micron), in contrast to the filtrates from the sensitive strains, which induced less migration of PMNLs (LI = 26.8 micron). This finding may explain previous observations that suggested that gentamicin-resistant strains of P. aeruginosa are less virulent than gentamicin-sensitive strains.

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Year:  1980        PMID： 6768811     DOI： 10.1093/infdis/141.4.507

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  5 in total

1.  Neutrophil functions in patients with fractures of the upper end of the femur.

Authors:  N G Papadopoulos; P E Lianou; G P Lyritis; T J Papavassiliou
Journal:  Calcif Tissue Int       Date:  1993-06       Impact factor: 4.333

2.  In vivo potentiation of polymorphonuclear leukocyte chemotaxis by clindamycin.

Authors:  A T Skoutelis; P E Lianou; H P Bassaris
Journal:  Infection       Date:  1993 Sep-Oct       Impact factor: 3.553

3.  Enhancement of polymorphonuclear leukocyte function against gram-positive aerobic organisms grown in the presence of lincomycin.

Authors:  H P Bassaris; P E Lianou; E G Votta; T Skoutelis; T Papavassiliou
Journal:  Infection       Date:  1984 Nov-Dec       Impact factor: 3.553

4.  Transient improvement of polymorphonuclear leukocyte function by splenectomy in beta-thalassemia.

Authors:  P E Lianou; H P Bassaris; A T Skoutelis; E G Votta; J T Papavassiliou; J P Phair
Journal:  Med Microbiol Immunol       Date:  1987       Impact factor: 3.402

5.  Gentamicin-resistantPseudomonas aeruginosa: Concepts regarding their evolution and attenuated virulence.

Authors:  J M Janda; D J Sheehan; A Das; E J Bottone
Journal:  Microb Ecol       Date:  1982-12       Impact factor: 4.552
  5 in total

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