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Literature DB >> 6768355

Degradation of [3H]chondroitin 4-sulphate and re-utilization of the [3H]hexosamine component by the isolated perfused rat liver.

A D MacNicholl, F S Wusteman, P J Winterburn, G M Powell, C G Curtis.

Abstract

Radiolabelled chondroitin 4-sulphate was isolated after incubation of rat rib cartilage with N-acetyl-D-[6-3H]galactosamine. After proteolytic digestion of the tissue with either papain or trypsin the released [3H]chondroitin 4-sulphate was added to an isolated perfused rat liver system. Analysis of perfusate after several hours perfusion showed that radiolabelled amino sugars were secreted by the liver in a low-molecular-weight form and as components of glycoproteins.

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Year: 1980 PMID： 6768355 PMCID： PMC1161528 DOI： 10.1042/bj1860279

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

11 in total

1. A modified uronic acid carbazole reaction.

Authors: T BITTER; H M MUIR
Journal: Anal Biochem Date: 1962-10 Impact factor: 3.365

2. Effect of tunicamycin on the secretion of serum proteins by primary cultures of rat and chick hepatocytes. Studies on transferrin, very low density lipoprotein, and serum albumin.

Authors: D K Struck; P B Siuta; M D Lane; W J Lennarz
Journal: J Biol Chem Date: 1978-08-10 Impact factor: 5.157

3. The metabolic fate of N-acetyl-D-[1-14C]galactosamine in isolated perfused rat liver.

Authors: A D MacNicoll; F S Wusteman; G M Powell; C G Curtis
Journal: Biochem Soc Trans Date: 1977 Impact factor: 5.407

4. Incorporation of D-[I-14C]galactosamine into serum proteins and tissues of the rat.

Authors: B N White; M R Shetlar; H M Shurley; J A Schilling
Journal: Biochim Biophys Acta Date: 1965-11-01

5. The metabolism of d-galactosamine and N-acetyl-d-galactosamine in rat liver.

Authors: F Maley; A L Tarentino; J F McGarrahan; R Delgiacco
Journal: Biochem J Date: 1968-05 Impact factor: 3.857

6. The glycosaminoglycans of human tracheobronchial cartilage.

Authors: R M Mason; F S Wusteman
Journal: Biochem J Date: 1970-12 Impact factor: 3.857

7. The degradation of intravenously injected chondroitin 4-sulphate in the rat.

Authors: K M Wood; F S Wusteman; C G Curtis
Journal: Biochem J Date: 1973-08 Impact factor: 3.857

8. Utilization by the isolated perfused rat liver of N-acetyl-D-[1-14C]galactosamine and N-[3H]acetyl-D-galactosamine for the biosynthesis of glycoproteins.

Authors: A D MacNicoll; F S Wusteman; G M Powell; C G Curtis
Journal: Biochem J Date: 1978-08-15 Impact factor: 3.857