Literature DB >> 6768309

Effect of protein cross-linking reagents on membrane currents of squid axon.

R Horn, M S Brodwick, D C Eaton.   

Abstract

The effects of the protein cross-linking reagents glutaraldehyde, tannic acid, and formaldehyde were examined in voltage-clamped and internally perfused squid axons. All three reagents reduced sodium and potassium currents and reduced or abolished sodium inactivation. Glutaraldehyde and tannic acid produced an alteration of potassium current kinetics.

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Year:  1980        PMID: 6768309     DOI: 10.1152/ajpcell.1980.238.3.C127

Source DB:  PubMed          Journal:  Am J Physiol        ISSN: 0002-9513


  7 in total

1.  Effects of channel cytoplasmic regions on the activation mechanisms of cardiac versus skeletal muscle Na(+) channels.

Authors:  E S Bennett
Journal:  Biophys J       Date:  1999-12       Impact factor: 4.033

2.  Voltage and temperature dependence of normal and chemically modified inactivation of sodium channels. Quantitative description by a cyclic three-state model.

Authors:  J Schmidtmayer
Journal:  Pflugers Arch       Date:  1989-07       Impact factor: 3.657

3.  Behaviour of chemically modified sodium channels in frog nerve supports a three-state model of inactivation.

Authors:  J Schmidtmayer
Journal:  Pflugers Arch       Date:  1985-05       Impact factor: 3.657

4.  Effects of millimolar concentrations of glutaraldehyde on the electrical properties of frog skin.

Authors:  D G Mărgineanu; W Van Driessche
Journal:  J Physiol       Date:  1990-08       Impact factor: 5.182

5.  The nonselective cation channel in the basolateral membrane of rat exocrine pancreas. Inhibition by 3',5-dichlorodiphenylamine-2-carboxylic acid (DCDPC) and activation by stilbene disulfonates.

Authors:  H Gögelein; B Pfannmüller
Journal:  Pflugers Arch       Date:  1989-01       Impact factor: 3.657

6.  A high-conductance anion channel in adult amphibian skeletal muscle.

Authors:  K H Woll; M D Leibowitz; B Neumcke; B Hille
Journal:  Pflugers Arch       Date:  1987-12       Impact factor: 3.657

7.  Modulation of aminopyridine block of potassium currents in squid axon.

Authors:  G E Kirsch; J Z Yeh; G S Oxford
Journal:  Biophys J       Date:  1986-10       Impact factor: 4.033

  7 in total

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