| Literature DB >> 6767543 |
H Schipper, B M McClarty, K E McRuer, R A Nash, C J Penney.
Abstract
Chagas' disease, or South American trypanosomiasis, is an endemic South American disease now being seen in Canada in both acute and chronic forms. It is characterized by an initial parasitemia that elicits a brisk immune response. Evidence is mounting that the debilitating chronic form, which is characterized by cardiac and visceral organ failure, results from antigenic cross-reactivity between the parasite and the human host, which generates an aberrant, destructive, cell-mediated immune response. Diagnosis, treatment and potential areas for investigation are discussed.Entities:
Mesh：
Year: 1980 PMID： 6767543 PMCID： PMC1801746
Source DB: PubMed Journal: Can Med Assoc J ISSN： 0008-4409 Impact factor: 8.262