Literature DB >> 6766222

The heart is a target organ for androgen.

H C McGill, V C Anselmo, J M Buchanan, P J Sheridan.   

Abstract

Autoradiographic and biochemical analyses of the hearts of female rhesus monkeys and baboons indicate that atrial and ventricular myocardial cells contain androgen receptors. Although the specific effects of nuclear uptake and retention of androgen on the function of heart muscle cells are not known, the presence of this receptor suggests that sex steroid hormones may affect myocardial function directly and may explain some of the peculiar differences in heart disease between men and women.

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Year:  1980        PMID: 6766222     DOI: 10.1126/science.6766222

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  18 in total

Review 1.  Steroid hormones and the cardiovascular system: direct actions of estradiol, progesterone, testosterone, gluco- and mineralcorticoids, and soltriol [vitamin D] on central nervous regulatory and peripheral tissues.

Authors:  W E Stumpf
Journal:  Experientia       Date:  1990-01-15

2.  Antiarrhythmic effect and its underlying ionic mechanism of 17beta-estradiol in cardiac myocytes.

Authors:  T Nakajima; K Iwasawa; H Oonuma; T Morita; A Goto; Y Wang; H Hazama
Journal:  Br J Pharmacol       Date:  1999-05       Impact factor: 8.739

Review 3.  Hormones and the neuromuscular control of courtship in the golden-collared manakin (Manacus vitellinus).

Authors:  Barney A Schlinger; Julia Barske; Lainy Day; Leonida Fusani; Matthew J Fuxjager
Journal:  Front Neuroendocrinol       Date:  2013-04-25       Impact factor: 8.606

4.  Menstrual cycle and ST height.

Authors:  Susanne Endres; Kenneth A Mayuga; Alessandro de Cristofaro; Taresh Taneja; Jeffrey J Goldberger; Alan H Kadish
Journal:  Ann Noninvasive Electrocardiol       Date:  2004-04       Impact factor: 1.468

5.  Ventricular structure, function, and focal fibrosis in anabolic steroid users: a CMR study.

Authors:  Peter J Angell; Tevfik F Ismail; Andrew Jabbour; Gillian Smith; Annette Dahl; Ricardo Wage; Greg Whyte; Daniel J Green; Sanjay Prasad; Keith George
Journal:  Eur J Appl Physiol       Date:  2014-01-28       Impact factor: 3.078

6.  Testosterone protects rat hearts against ischaemic insults by enhancing the effects of alpha(1)-adrenoceptor stimulation.

Authors:  S Tsang; S Wu; J Liu; T M Wong
Journal:  Br J Pharmacol       Date:  2007-12-24       Impact factor: 8.739

7.  Autoradiographic localization of sex steroid hormones in the lymphatic organs of baboons.

Authors:  F J Weaker; P J Sheridan
Journal:  Cell Tissue Res       Date:  1983       Impact factor: 5.249

8.  Autoradiographic demonstration of binding sites for oestradiol and dihydrotestosterone in the urinary tract of male and female baboons.

Authors:  F J Weaker; D C Herbert; P J Sheridan
Journal:  Urol Res       Date:  1983

9.  Stimulation of N-terminal truncated isoform of androgen receptor stabilizes human ether-á-go-go-related gene-encoded potassium channel protein via activation of extracellular signal regulated kinase 1/2.

Authors:  Zhi-Yuan Wu; Kun Chen; Bernard Haendler; Thomas V McDonald; Jin-Song Bian
Journal:  Endocrinology       Date:  2008-07-03       Impact factor: 4.736

10.  Effect of 17 beta-oestradiol on contraction, Ca2+ current and intracellular free Ca2+ in guinea-pig isolated cardiac myocytes.

Authors:  C Jiang; P A Poole-Wilson; P M Sarrel; S Mochizuki; P Collins; K T MacLeod
Journal:  Br J Pharmacol       Date:  1992-07       Impact factor: 8.739

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