Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Effect of riboflavin on monoamine oxidase activity in cultured neuroblastoma cells.

Literature DB >> 6765737

Effect of riboflavin on monoamine oxidase activity in cultured neuroblastoma cells.

V Bonnefil¹, C M Castiglione, R M Cawthon, X O Breakefield.

Abstract

Monoamine oxidase (MAO) depends on a covalently attached FAD cofactor for activity. Activity is depressed in mouse neuroblastoma cells (N1E-115) grown in synthetic N2 medium lacking riboflavin. MAO activity in depleted cells is stimulated by added riboflavin, and this recovery is blocked by inhibitors of RNA and protein synthesis, and not by an inhibitor of protein glycosylation Recovery from riboflavin depletion appears to depend upon new RNA and protein synthesis, and not on the addition of FAD cofactor to an inactive MAO precursor.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1981 PMID： 6765737 DOI： 10.1007/bf00716270

Source DB: PubMed Journal: Cell Mol Neurobiol ISSN： 0272-4340 Impact factor: 5.046

30 in total

1. A SENSITIVE AND SPECIFIC ASSAY FOR THE ESTIMATION OF MONOAMINE OXIDASE.

Authors: R J WURTMAN; J AXELROD
Journal: Biochem Pharmacol Date: 1963-12 Impact factor: 5.858

2. Monoamine oxidase A and B in cultured cells.

Authors: M Hawkins; X O Breakefield
Journal: J Neurochem Date: 1978-06 Impact factor: 5.372

3. Proteins with covalently-bound flavin in rat liver mitochondria.

Authors: M Sato; N Ohishi; M Nishikimi; K Yagi
Journal: Biochem Biophys Res Commun Date: 1977-10-10 Impact factor: 3.575

Review 4. Substrate-selective monoamine oxidases--inhibitor, tissue, species and functional differences.

Authors: D L Murphy
Journal: Biochem Pharmacol Date: 1978 Impact factor: 5.858

5. Polypeptide bound to the host RNA polymerase is specified by T4 control gene 33.

Authors: H R Horvitz
Journal: Nat New Biol Date: 1973-08-01

6. Monoamine oxidase from beef liver mitochondria: simplified isolation procedure, properties, and determination of its cysteinyl flavin content.

Authors: J I Salach
Journal: Arch Biochem Biophys Date: 1979-01 Impact factor: 4.013

Effect of riboflavin on monoamine oxidase activity in cultured neuroblastoma cells.

1. A SENSITIVE AND SPECIFIC ASSAY FOR THE ESTIMATION OF MONOAMINE OXIDASE.

2. Monoamine oxidase A and B in cultured cells.

3. Proteins with covalently-bound flavin in rat liver mitochondria.

Review 4. Substrate-selective monoamine oxidases--inhibitor, tissue, species and functional differences.

5. Polypeptide bound to the host RNA polymerase is specified by T4 control gene 33.

6. Monoamine oxidase from beef liver mitochondria: simplified isolation procedure, properties, and determination of its cysteinyl flavin content.

7. The labeling in vivo of monoamine oxidase by 14 C-pargyline: a tool for studying the synthesis of the enzyme.

8. A new method for serum iron and total iron-binding capacity by atomic absorption spectrophotometry.

9. Iron content and spectral properties of highly purified bovine liver monoamine oxidase.

10. Dexamethasone selectively increases monoamine oxidase type A in human skin fibroblasts.

1. Monoamine oxidases A and B are differentially regulated by glucocorticoids and "aging" in human skin fibroblasts.