Literature DB >> 6765182

Problems of delivery of drugs to the brain.

N Bodor, M E Brewster.   

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Year:  1982        PMID： 6765182     DOI： 10.1016/0163-7258(82)90073-0

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN： 0163-7258            Impact factor:   12.310


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  18 in total

1.  A redox-based system that enhances delivery of estradiol to the brain: pharmacokinetic evaluation in the dog.

Authors:  K Dietzel; V Keuth; K S Estes; M E Brewster; R M Clemmons; R Vistelle; N S Bodor; H Derendorf
Journal:  Pharm Res       Date:  1990-08       Impact factor: 4.200

Review 2.  Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting: implications of the barriers between blood and brain.

Authors:  Elizabeth C M de Lange; Meindert Danhof
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

3.  Improved Delivery Through Biological Membranes. XXIV. Synthesis, in Vitro Studies, and in Vivo Characterization of Brain-Specific and Sustained Progestin Delivery Systems.

Authors:  M E Brewster; K S Estes; N Bodor
Journal:  Pharm Res       Date:  1986-10       Impact factor: 4.200

4.  Specific differences in tolerance to exogenous berberine among plant cell cultures.

Authors:  H Sato; Y Kobayashi; H Fukui; M Tabata
Journal:  Plant Cell Rep       Date:  1990-07       Impact factor: 4.570

5.  In vitro and in vivo investigations of dihydropyridine-based chemical delivery systems for anticonvulsants.

Authors:  A V Boddy; K Zhang; F Lepage; F Tombret; J G Slatter; T A Baillie; R H Levy
Journal:  Pharm Res       Date:  1991-06       Impact factor: 4.200

6.  A redox-based chemical delivery system that enhances estradiol distribution to the brain: disposition studies in the rat.

Authors:  K S Estes; V Keuth; K Dietzel; M E Brewster; N S Bodor; H Derendorf
Journal:  Pharm Res       Date:  1991-09       Impact factor: 4.200

7.  High-performance liquid chromatographic assay of a central nervous system (CNS)-directed estradiol chemical delivery system and its application after intravenous administration to rats.

Authors:  G Mullersman; H Derendorf; M E Brewster; K S Estes; N Bodor
Journal:  Pharm Res       Date:  1988-03       Impact factor: 4.200

8.  Dose and time-course evaluation of a redox-based estradiol-chemical delivery system for the brain. I. Tissue distribution.

Authors:  M H Rahimy; J W Simpkins; N Bodor
Journal:  Pharm Res       Date:  1990-10       Impact factor: 4.200

9.  Improved delivery through biological membranes. XLV. Synthesis, physical-chemical evaluation, and brain uptake studies of 2-chloroethyl nitrosourea delivery systems.

Authors:  K Raghavan; T Loftsson; M E Brewster; N Bodor
Journal:  Pharm Res       Date:  1992-06       Impact factor: 4.200

10.  Application of intracerebral microdialysis to study regional distribution kinetics of drugs in rat brain.

Authors:  E C de Lange; M R Bouw; J W Mandema; M Danhof; A G de Boer; D D Breimer
Journal:  Br J Pharmacol       Date:  1995-11       Impact factor: 8.739
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