Literature DB >> 6764829

Multicentre clinical trials: Bradford Hill's contributions and some subsequent developments.

J L Fleiss.   

Abstract

Most large comparative trials of therapeutic agents are now conducted as multicentre studies. Some of the major studies designed by Bradford Hill were also multicentre, and his methods of design and conduct remain valid today, even though improved methods for analysing the data have appeared subsequently.

Mesh:

Year:  1982        PMID: 6764829     DOI: 10.1002/sim.4780010413

Source DB:  PubMed          Journal:  Stat Med        ISSN: 0277-6715            Impact factor:   2.373


  2 in total

1.  The mortality risk associated with digitalis treatment after myocardial infarction.

Authors:  A J Moss; J T Bigger; E Carleen; J L Fleiss; C L Odoroff; L Rolnitzky; T Therneau
Journal:  Cardiovasc Drugs Ther       Date:  1987-08       Impact factor: 3.727

2.  Propionyl-L-Carnitine versus Pentoxifylline : Improvement in Walking Capacity in Patients with Intermittent Claudication.

Authors:  Antonio Strano
Journal:  Clin Drug Investig       Date:  2002-11       Impact factor: 2.859

  2 in total

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