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Literature DB >> 6763817

Window panes of eternity. Health, disease, and inherited risk.

Abstract

Personal health reflects harmony between individual and experience; it is optimal homeostasis. Disease is an outcome of incongruity leading to dishomeostasis. Relative to earlier times, disease in modern society has higher "heritability" (in the broad meaning of the term). Inherited risks are facts compatible with anticipation and prevention of disease. This viewpoint has major implications for medical practice, deployment of health services, themes of research, and education of health care personnel and citizens.

Entities: Disease

Mesh：

Year: 1982 PMID： 6763817 PMCID： PMC2596554

Source DB: PubMed Journal: Yale J Biol Med ISSN： 0044-0086

73 in total

Review 4. X-linked mental retardation.

Authors: G Turner; J M Opitz
Journal: Am J Med Genet Date: 1980

9. Heritable fragile sites on human chromosomes. VIII. Preliminary population cytogenetic data on the folic-acid-sensitive fragile sites.

Authors: G R Sutherland
Journal: Am J Hum Genet Date: 1982-05 Impact factor: 11.025

Review 10. Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

Authors: D Botstein; R L White; M Skolnick; R W Davis
Journal: Am J Hum Genet Date: 1980-05 Impact factor: 11.025

2 in total

Review 1. The salience of Garrod's 'molecular groupings' and 'Inborn Factors in Disease'.

Authors: C R Scriver
Journal: J Inherit Metab Dis Date: 1989 Impact factor: 4.982

2. The 'morbid anatomy' of the human genome: tracing the observational and representational approaches of postwar genetics and biomedicine the William Bynum Prize Essay.

Authors: Andrew J Hogan
Journal: Med Hist Date: 2014-07 Impact factor: 1.419

2 in total

Window panes of eternity. Health, disease, and inherited risk.

1. Genetic linkage and hemosiderosis.

2. The William Allan Memorial Award Lecture. A place for genetics in health education, and vice versa.

3. Scientific basis for the support of biomedical science.

Review 4. X-linked mental retardation.

5. The practice of medicine in 18th-century Massachusetts: a bicentennial perspective.

6. A highly polymorphic locus in human DNA.

7. Phenylketonuria: epitome of human biochemical genetics (second of two parts).

8. Genetics of hemochromatosis.

9. Heritable fragile sites on human chromosomes. VIII. Preliminary population cytogenetic data on the folic-acid-sensitive fragile sites.

Review 10. Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

Review 1. The salience of Garrod's 'molecular groupings' and 'Inborn Factors in Disease'.

2. The 'morbid anatomy' of the human genome: tracing the observational and representational approaches of postwar genetics and biomedicine the William Bynum Prize Essay.