Literature DB >> 6763275

Relationship of specific granules to renin activity in the myocardium.

M Cantin, A M Michelakis, H Ong, M Ballak, J Beuzeron, S Benchimol.   

Abstract

In this study we have shown that sodium deprivation of rats increased the number of specific granules and renin activity in atria. Sodium loading and DOCA treatment were found to lower the number of granules and renin activity. Renin activity which is present in both atria and ventricles is not localized in specific granules, as shown by ultracentrifugation and immunocytochemistry. Although this renin activity was partially abolished by preincubation with specific antiserum, the present results do not rule out the possibility that the activity is due to cathepsin D.

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Year:  1982        PMID: 6763275     DOI: 10.1007/978-1-4899-5561-6_49

Source DB:  PubMed          Journal:  Adv Myocardiol        ISSN: 0270-4056


  3 in total

1.  Atrial-specific granules in the hearts of normal and water-deprived rats.

Authors:  H Toshimori; K Toshimori; S Matsukura; C Oura; H Matsuo
Journal:  Cell Tissue Res       Date:  1988-09       Impact factor: 5.249

Review 2.  Biologically active atrial peptides.

Authors:  B J Ballerman; B M Brenner
Journal:  J Clin Invest       Date:  1985-12       Impact factor: 14.808

Review 3.  Atrial natriuretic peptide in the central nervous system of the rat.

Authors:  G Skofitsch; D M Jacobowitz
Journal:  Cell Mol Neurobiol       Date:  1988-12       Impact factor: 5.046

  3 in total

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