Literature DB >> 6761561

Chloroquine-resistant Plasmodium falciparum malaria in Vanuatu.

D K Bowden, P Bastien, F P Douglas, J W Muir, E Tambisari.   

Abstract

Cases of malaria caused by Plasmodium falciparum resistant to chloroquine treatment have been probably occurring in Vanuatu for many years. In this survey, seven patients with P. falciparum malaria were investigated for evidence of resistance to chloroquine. In-vitro resistance to chloroquine was demonstrated in four. Two further patients who had clinical resistance to chloroquine treatment developed cerebral malaria. It is of interest that one of these patients was subsequently successfully treated with mepacrine. Two additional cases are cited as examples of resistance to chloroquine treatment encountered in the past.

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Year:  1982        PMID： 6761561

Source DB:  PubMed          Journal:  Med J Aust        ISSN： 0025-729X            Impact factor:   7.738


  5 in total

1.  Active case detection, treatment of falciparum malaria with combined chloroquine and sulphadoxine/pyrimethamine and vivax malaria with chloroquine and molecular markers of anti-malarial resistance in the Republic of Vanuatu.

Authors:  Michael H Kinzer; Krisin Chand; Hasan Basri; Edith R Lederman; Augustina I Susanti; Iqbal Elyazar; George Taleo; William O Rogers; Michael J Bangs; Jason D Maguire
Journal:  Malar J       Date:  2010-04-06       Impact factor: 2.979

2.  Malaria on isolated Melanesian islands prior to the initiation of malaria elimination activities.

Authors: 
Journal:  Malar J       Date:  2010-07-26       Impact factor: 2.979

3.  Diversity of Plasmodium falciparum chloroquine resistance transporter (pfcrt) exon 2 haplotypes in the Pacific from 1959 to 1979.

Authors:  Chim W Chan; Rita Spathis; Dana M Reiff; Stacy E McGrath; Ralph M Garruto; J Koji Lum
Journal:  PLoS One       Date:  2012-01-17       Impact factor: 3.240

4.  Genetic mutations in Plasmodium falciparum and Plasmodium vivax dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) in Vanuatu and Solomon Islands prior to the introduction of artemisinin combination therapy.

Authors:  Karryn J Gresty; Karen-Ann Gray; Albino Bobogare; Lyndes Wini; George Taleo; Jeffrey Hii; Qin Cheng; Norman C Waters
Journal:  Malar J       Date:  2014-10-14       Impact factor: 2.979

5.  Genetic mutations in pfcrt and pfmdr1 at the time of artemisinin combination therapy introduction in South Pacific islands of Vanuatu and Solomon Islands.

Authors:  Karryn J Gresty; Karen-Ann Gray; Albino Bobogare; George Taleo; Jeffrey Hii; Lyndes Wini; Qin Cheng; Norman C Waters
Journal:  Malar J       Date:  2014-10-15       Impact factor: 2.979
  5 in total

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