| Literature DB >> 6759797 |
C N Boyd, R C Ramberg, E D Thomas.
Abstract
A total of 243 patients with acute leukemia received a marrow graft from a donor of the opposite sex. Seventy-five patients subsequently relapsed, and specimens of the recurrent leukemia cells were available for cytogenetic analysis in 54. Three relapses were in donor-type cells. Four patients whose relapses were in host-type cells showed a cytogenic abnormality that differed from the original leukemic clone. We conclude that a 'new' leukemia in donor cells, and possibly in host cells, constitutes a small but significant fraction of recurrent leukemia after marrow grafting.Entities:
Mesh:
Year: 1982 PMID: 6759797 DOI: 10.1016/0145-2126(82)90067-4
Source DB: PubMed Journal: Leuk Res ISSN: 0145-2126 Impact factor: 3.156