Literature DB >> 6759533

Formalin-killed versus heat-killed Legionella pneumophila serogroup 1 antigen in the indirect immunofluorescence assay for legionellosis.

H W Wilkinson, B J Brake.   

Abstract

Indirect immunofluorescence assay titers of human sera obtained against the Legionella pneumophila serogroup 1 antigen (Philadelphia 1 strain) killed with 10% Formalin showed a tendency to be lower than those obtained against the reference heat-killed antigen (geometric mean titer of 194 and 370, respectively) when all other variables in the test were held constant. Test results were interpreted the same for 96% of 60 paired sera if the cutoff level used to interpret a positive test result for the formalinized antigen was lowered by one twofold dilution factor.

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Year:  1982        PMID： 6759533      PMCID： PMC272517          DOI： 10.1128/jcm.16.5.979-981.1982

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  9 in total

1.  Detection of Legionnaires disease bacteria by direct immunofluorescent staining.

Authors:  W B Cherry; B Pittman; P P Harris; G A Hebert; B M Thomason; L Thacker; R E Weaver
Journal:  J Clin Microbiol       Date:  1978-09       Impact factor: 5.948

2.  Prevalence of antibody to Legionella pneumophila in middle-aged and elderly Americans.

Authors:  G Storch; P S Hayes; D L Hill; W B Baine
Journal:  J Infect Dis       Date:  1979-11       Impact factor: 5.226

3.  Measure of immunoglobulin G-, M-, and A-specific titers against Legionella pneumophila and inhibition of titers against nonspecific, gram-negative bacterial antigens in the indirect immunofluorescence test for legionellosis.

Authors:  H W Wilkinson; C E Farshy; B J Fikes; D D Cruce; L P Yealy
Journal:  J Clin Microbiol       Date:  1979-11       Impact factor: 5.948

4.  Legionnaires' disease in New York City, August-September 1978.

Authors:  L G Cordes; W D Goldman; J S Marr; S M Friedman; J D Band; E O Rothschild; H Kravitz; J C Feeley; D W Fraser
Journal:  Bull N Y Acad Med       Date:  1980-06

5.  False positive reactions in the indirect fluorescent antibody test for Legionnaires' disease eliminated by use of formolised yolk-sac antigen.

Authors:  A G Taylor; T G Harrison; M W Dighero; C M Bradstreet
Journal:  Ann Intern Med       Date:  1979-04       Impact factor: 25.391

6.  Legionnaires' disease: isolation of a bacterium and demonstration of its role in other respiratory disease.

Authors:  J E McDade; C C Shepard; D W Fraser; T R Tsai; M A Redus; W R Dowdle
Journal:  N Engl J Med       Date:  1977-12-01       Impact factor: 91.245

7.  Validation of Legionella pneumophila indirect immunofluorescence assay with epidemic sera.

Authors:  H W Wilkinson; D D Cruce; C V Broome
Journal:  J Clin Microbiol       Date:  1981-01       Impact factor: 5.948

8.  Indirect immunofluorescence test for serodiagnosis of Legionnaires disease: evidence for serogroup diversity of Legionnaires disease bacterial antigens and for multiple specificity of human antibodies.

Authors:  H W Wilkinson; B J Fikes; D D Cruce
Journal:  J Clin Microbiol       Date:  1979-03       Impact factor: 5.948

9.  Legionnaires' disease serology. Effect of antigen preparation on specificity and sensitivity of the indirect fluorescent antibody test.

Authors:  G L Lattimer; B A Cepil
Journal:  J Clin Pathol       Date:  1980-06       Impact factor: 3.411
  9 in total
  10 in total

Review 1.  Laboratory diagnosis of infections caused by legionellae.

Authors:  P H Edelstein
Journal:  Eur J Clin Microbiol       Date:  1987-02       Impact factor: 3.267

Review 2.  Legionnaires disease: historical perspective.

Authors:  W C Winn
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

3.  Comparison of phenol- and heat-killed antigens in the indirect immunofluorescence test for serodiagnosis of Legionella pneumophila group 1 infections.

Authors:  M C Pastoris; S Ciarrocchi; A Di Capua; A M Temperanza
Journal:  J Clin Microbiol       Date:  1984-10       Impact factor: 5.948

4.  Factors influencing the reactivity of Legionella antigens in immunofluorescence tests.

Authors:  R F Benson; G B Malcolm; L Pine; W K Harrell
Journal:  J Clin Microbiol       Date:  1983-05       Impact factor: 5.948

5.  Legionella pneumophila in aerosols from shower baths.

Authors:  P J Dennis; A E Wright; D A Rutter; J E Death; B P Jones
Journal:  J Hyg (Lond)       Date:  1984-10

6.  Proximity of the home to a cooling tower and risk of non-outbreak Legionnaires' disease.

Authors:  R S Bhopal; R J Fallon; E C Buist; R J Black; J D Urquhart
Journal:  BMJ       Date:  1991-02-16

Review 7.  Legionella and Legionnaires' disease: 25 years of investigation.

Authors:  Barry S Fields; Robert F Benson; Richard E Besser
Journal:  Clin Microbiol Rev       Date:  2002-07       Impact factor: 26.132

8.  Lesion formation and antibody response induced by papillomatous digital dermatitis-associated spirochetes in a murine abscess model.

Authors:  Margaret K Elliott; David P Alt; Richard L Zuerner
Journal:  Infect Immun       Date:  2007-06-25       Impact factor: 3.441

9.  Serological differences in Legionella pneumophila infections.

Authors:  J F Plouffe; G E Bollin; M F Para; K A Kelly
Journal:  J Clin Microbiol       Date:  1984-12       Impact factor: 5.948

10.  Cell-mediated immunity in Legionnaires' disease.

Authors:  M A Horwitz
Journal:  J Clin Invest       Date:  1983-06       Impact factor: 14.808
  10 in total

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