| Literature DB >> 6757030 |
P A Svendsen, T Lauritzen, U Søegaard, J Nerup.
Abstract
Since glucose control and glycosylated haemoglobin varies asyncroneously, we have studied the steady-state relationship between these two factors. In Type 1 (insulin-dependent) diabetic patients with a constant haemoglobin A1c during the preceding 2 years, 15 ambulatory blood glucose profiles during a 5-week period showed a constant glucose level and provided a precise estimate of the mean blood glucose concentration. In addition, we studied 15 non-diabetic subjects who provided three glucose profiles and had one haemoglobin A1c determination performed. A good correlation was found for a curvilinear relationship (haemoglobin A1c = 2.07 X mean blood glucose0.596, r = 0.98). This close relationship indicates that glycosylated haemoglobin is a valuable, but not very sensitive, index of glucose control.Entities:
Mesh:
Substances:
Year: 1982 PMID: 6757030 DOI: 10.1007/bf00260951
Source DB: PubMed Journal: Diabetologia ISSN: 0012-186X Impact factor: 10.122