| Literature DB >> 6756620 |
A J Forman, S D Acres, R A Kapitany, M L Buckley, D W Stainer, M A Maxwell.
Abstract
K99 antigen in Escherichia coli whole cell bacterins was immunogenic in rabbits and mice. Mice vaccinated subcutaneously and bled three weeks later had a serum antibody response which was dose dependent. The dose response on dilution of bacterins was shown to be mainly due to dilution of K99 antigen, rather than the reduction in adjuvant or bacterial cell concentration. The procedure appears to be a satisfactory one for immunogenicity testing of bacterins containing K99 antigen.Entities:
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Year: 1982 PMID： 6756620 PMCID： PMC1320310
Source DB: PubMed Journal: Can J Comp Med ISSN： 0008-4050