Literature DB >> 675552

Congenital deformities produced in hamsters by potato sprouts.

R F Keeler, S Young, D Brown, G F Stallknecht, D Douglas.   

Abstract

Dried gound potato sprout preparations from seven varieties produced congenital deformities in one strain of hamsters. Incidence of affected litters varied from 8 to 25%, depending on potato variety. Certain steroidal solanum and veratrum alkaloids produced similar defects. Neither peel nor tuber material was teratogenic from one of the potato varieties with highly teratogenic sprouts.

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Year:  1978        PMID: 675552     DOI: 10.1002/tera.1420170311

Source DB:  PubMed          Journal:  Teratology        ISSN: 0040-3709


  3 in total

1.  Wnt/PCP signalling cascade disruption by JNK inhibition as a potential mechanism underlying the teratogenic effects of potato glycoalkaloids.

Authors:  Andrea Cuschieri; Jean Calleja-Agius
Journal:  Mol Biol Rep       Date:  2020-10-24       Impact factor: 2.316

2.  Cyclopamine and related steroidal alkaloid teratogens: their occurrence, structural relationship, and biologic effects.

Authors:  R F Keeler
Journal:  Lipids       Date:  1978-10       Impact factor: 1.880

3.  Maternal periconceptional consumption of sprouted potato and risks of neural tube defects and orofacial clefts.

Authors:  Wenli Ni; Tian Tian; Le Zhang; Zhiwen Li; Linlin Wang; Aiguo Ren
Journal:  Nutr J       Date:  2018-11-28       Impact factor: 3.271

  3 in total

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