Literature DB >> 6753119

Pirenzepine in non-ulcer dyspepsia. A double-blind, placebo controlled trial.

P R Dal Monte, N D'Imperio, P Accardo, S Daniotti.   

Abstract

Fifty patients (with non-ulcer dyspepsia) were admitted to a double-blind, placebo-controlled trial to study the effects of pirenzepine (100 mg/daily) on non-ulcer dyspepsia. Ten patients did not complete the trial. After 4 weeks of treatment, statistically significant improvement (P less than 0.001) was observed endoscopically in the pirenzepine group. The relief of dyspepsia was significantly greater in the pirenzepine-treated group. The tolerability of pirenzepine was good.

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Year:  1982        PMID： 6753119

Source DB:  PubMed          Journal:  Scand J Gastroenterol Suppl        ISSN： 0085-5928


  4 in total

Review 1.  An approach to dyspepsia in the ambulatory care setting: evaluation based on risk stratification.

Authors:  S C Zell; M Budhraja
Journal:  J Gen Intern Med       Date:  1989 Mar-Apr       Impact factor: 5.128

2.  Effect of colloidal bismuth subcitrate on symptoms and gastric histology in non-ulcer dyspepsia. A double blind placebo controlled study.

Authors:  J Y Kang; H H Tay; A Wee; R Guan; M V Math; I Yap
Journal:  Gut       Date:  1990-04       Impact factor: 23.059

Review 3.  Functional dyspepsia. Current treatment recommendations.

Authors:  Gerald Holtmann; Nicholas J Talley
Journal:  Drugs       Date:  1993-06       Impact factor: 9.546

Review 4.  Pirenzepine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in peptic ulcer disease and other allied diseases.

Authors:  A A Carmine; R N Brogden
Journal:  Drugs       Date:  1985-08       Impact factor: 9.546
  4 in total

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