Literature DB >> 6752972

Kinetics of pharmacologic response.

N H Holford, L B Sheiner.   

Abstract

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Year:  1982        PMID： 6752972     DOI： 10.1016/0163-7258(82)90051-1

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN： 0163-7258            Impact factor:   12.310


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  116 in total

1.  Rate of change of blood concentrations is a major determinant of the pharmacodynamics of midazolam in rats.

Authors:  A Cleton; D Mazee; R A Voskuyl; M Danhof
Journal:  Br J Pharmacol       Date:  1999-05       Impact factor: 8.739

2.  Peripheral link model as an alternative for pharmacokinetic-pharmacodynamic modeling of drugs having a very short elimination half-life.

Authors:  J Laurin; F Donati; F Nekka; F Varin
Journal:  J Pharmacokinet Pharmacodyn       Date:  2001-02       Impact factor: 2.745

3.  All half-lives are wrong, but some half-lives are useful.

Authors:  J G Wright; A V Boddy
Journal:  Clin Pharmacokinet       Date:  2001       Impact factor: 6.447

4.  Use of sensitivity functions to characterise and compare the forgiveness of drugs.

Authors:  Patrice Nony; Jean-Pierre Boissel
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

5.  Modeling of pharmacokinetic/pharmacodynamic (PK/PD) relationships: concepts and perspectives.

Authors:  H Derendorf; B Meibohm
Journal:  Pharm Res       Date:  1999-02       Impact factor: 4.200

6.  Pharmacokinetic/pharmacodynamic integration in drug development and dosage-regimen optimization for veterinary medicine.

Authors:  Pierre-Louis Toutain
Journal:  AAPS PharmSci       Date:  2002

7.  Pharmacokinetic-pharmacodynamic modelling of the EEG effects of midazolam in individual rats: influence of rate and route of administration.

Authors:  J W Mandema; E Tukker; M Danhof
Journal:  Br J Pharmacol       Date:  1991-03       Impact factor: 8.739

Review 8.  Nonlinear dynamics in clinical pharmacology: the paradigm of cortisol secretion and suppression.

Authors:  Aristides Dokoumetzidis; Athanassios Iliadis; Panos Macheras
Journal:  Br J Clin Pharmacol       Date:  2002-07       Impact factor: 4.335

9.  Inotropic effect of digoxin in humans: mechanistic pharmacokinetic/pharmacodynamic model based on slow receptor binding.

Authors:  Michael Weiss; Wonku Kang
Journal:  Pharm Res       Date:  2004-02       Impact factor: 4.200

Review 10.  Perspective: Implications of Ligand-Receptor Binding Kinetics for Therapeutic Targeting of G Protein-Coupled Receptors.

Authors:  Wijnand J C van der Velden; Laura H Heitman; Mette M Rosenkilde
Journal:  ACS Pharmacol Transl Sci       Date:  2020-03-18
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