Literature DB >> 6751906

Increase in circulating basement membrane antigens in diabetic rats and effects of insulin treatment.

J Risteli, K E Draeger, G Regitz, H P Neubauer.   

Abstract

The serum concentrations of two recently discovered antigens derived from basement membranes (7-S collagen and laminin P2) were assayed in streptozotocin-diabetic rats as possible indicators of basement membrane metabolism. The concentrations of both increased significantly after 8 weeks of diabetes, and that of 7-S collagen at least remained elevated up to 24 weeks. Treatment with insulin, which did not correct the metabolic disturbances, inhibited the increase in the concentration of 7-S collagen in serum, but did not completely normalize that of laminin P2.

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Year:  1982        PMID： 6751906     DOI： 10.1007/bf00252853

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  13 in total

1.  Laminin--a glycoprotein from basement membranes.

Authors:  R Timpl; H Rohde; P G Robey; S I Rennard; J M Foidart; G R Martin
Journal:  J Biol Chem       Date:  1979-10-10       Impact factor: 5.157

Review 2.  Current status of capillary basement-membrane disease in diabetes mellitus.

Authors:  J R Williamson; C Kilo
Journal:  Diabetes       Date:  1977-01       Impact factor: 9.461

3.  Macromolecular structure of basement membrane collagens.

Authors:  K Kühn; H Wiedemann; R Timpl; J Risteli; H Dieringer; T Voss; R W Glanville
Journal:  FEBS Lett       Date:  1981-03-09       Impact factor: 4.124

4.  Type IV collagens' isolation and characterization of 7S collagen from human kidney, liver and lung.

Authors:  S N Dixit; J M Stuart; J M Seyer; J Risteli; R Timpl; A H Kang
Journal:  Coll Relat Res       Date:  1981-11

5.  Characterization of pepsin fragments of laminin in a tumor basement membrane. Evidence for the existence of related proteins.

Authors:  H Rohde; H P Bächinger; R Timpl
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1980-11

6.  Isolation and characterization of pepsin fragments of laminin from human placental and renal basement membranes.

Authors:  L Risteli; R Timpl
Journal:  Biochem J       Date:  1981-03-01       Impact factor: 3.857

7.  Immunological characterization of the 7-S domain of type IV collagens.

Authors:  J Risteli; G Wick; R Timpl
Journal:  Coll Relat Res       Date:  1981-09

8.  Basement membrane research.

Authors:  L Risteli; J Risteli
Journal:  Med Biol       Date:  1981-08

9.  Sensitive radioimmunoassays for 7 S collagen and laminin: application to serum and tissue studies of basement membranes.

Authors:  J Risteli; H Rohde; R Timpl
Journal:  Anal Biochem       Date:  1981-05-15       Impact factor: 3.365

10.  Laboratory animals exhibiting obesity and diabetes syndromes.

Authors:  L Herberg; D L Coleman
Journal:  Metabolism       Date:  1977-01       Impact factor: 8.694
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  12 in total

1.  Serum concentrations of laminin P1 in diabetics with advanced nephropathy.

Authors:  P Pietschmann; G Schernthaner; C H Schnack; S Gaube
Journal:  J Clin Pathol       Date:  1988-09       Impact factor: 3.411

2.  Glomerular basement membrane synthesis and serum concentration of type IV collagen in streptozotocin-diabetic rats.

Authors:  C Hasslacher; R Reichenbacher; F Gechter; R Timpl
Journal:  Diabetologia       Date:  1984-02       Impact factor: 10.122

3.  Increased serum laminin and angiogenin concentrations in patients with peripheral arterial occlusive disease.

Authors:  H Burgmann; U Hollenstein; T Maca; K Zedwitz-Liebenstein; F Thalhammer; R Koppensteiner; H Ehringer; W Graninger
Journal:  J Clin Pathol       Date:  1996-06       Impact factor: 3.411

4.  Increased deposition of basement membrane macromolecules in specific vessels of the spontaneously hypertensive rat.

Authors:  P G McGuire; D G Brocks; P D Killen; R W Orkin
Journal:  Am J Pathol       Date:  1989-08       Impact factor: 4.307

5.  Uptake and degradation in vivo and in vitro of laminin and nidogen by rat liver cells.

Authors:  B Smedsrød; M Paulsson; S Johansson
Journal:  Biochem J       Date:  1989-07-01       Impact factor: 3.857

6.  Influence of hypertension on serum concentration of type IV collagen antigens in streptozotocin-diabetic and non-diabetic rats.

Authors:  C Hasslacher; D Brocks; J Mann; G Mall; R Waldherr
Journal:  Diabetologia       Date:  1987-05       Impact factor: 10.122

7.  Type IV collagen antigens in serum of diabetic rats: a marker for basement membrane collagen biosynthesis.

Authors:  D G Brocks; H P Neubauer; H Strecker
Journal:  Diabetologia       Date:  1985-12       Impact factor: 10.122

8.  Concentrations of 7S collagen and laminin P1 in sera of patients with diabetes mellitus.

Authors:  B Högemann; B Voss; F J Altenwerth; M Schneider; J Rauterberg; U Gerlach
Journal:  Klin Wochenschr       Date:  1986-04-15

9.  Alterations in basement membrane immunoreactivity of the diabetic retina in three diabetic mouse models.

Authors:  E Abari; N Kociok; U Hartmann; I Semkova; M Paulsson; A Lo; A M Joussen
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-12-21       Impact factor: 3.117

10.  Radioimmunoassay for the carboxy-terminal cross-linking domain of type IV (basement membrane) procollagen in body fluids. Characterization and application to collagen type IV metabolism in fibrotic liver disease.

Authors:  D Schuppan; M Besser; R Schwarting; E G Hahn
Journal:  J Clin Invest       Date:  1986-07       Impact factor: 14.808
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