Literature DB >> 6751754

A review of possible toxicity of di-2-ethylhexylphthalate (DEHP) in plastic intravenous containers: effects on reproduction.

A F Kaul, P F Souney, R Osathanondh.   

Abstract

Many containers for intravenous solutions are made with plasticized polyvinyl chloride, the common form of which is di-2-ethylhexylphthalate (DEHP). Extraction of DEHP into blood and plasma stored in such plastic containers can occur, and harmful effects of DEHP in the human body consequently have been suggested. Reports on toxicity of DEHP in animals during pregnancy and the developmental period are critically reviewed.

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Year:  1982        PMID： 6751754     DOI： 10.1177/106002808201600908

Source DB:  PubMed          Journal:  Drug Intell Clin Pharm        ISSN： 0012-6578


  15 in total

Review 1.  Impact of environmental exposures on ovarian function and role of xenobiotic metabolism during ovotoxicity.

Authors:  Poulomi Bhattacharya; Aileen F Keating
Journal:  Toxicol Appl Pharmacol       Date:  2012-04-13       Impact factor: 4.219

2.  Maternal phthalate exposure during early pregnancy and at delivery in relation to gestational age and size at birth: A preliminary analysis.

Authors:  Deborah J Watkins; Samantha Milewski; Steven E Domino; John D Meeker; Vasantha Padmanabhan
Journal:  Reprod Toxicol       Date:  2016-06-25       Impact factor: 3.143

3.  Novel organization of the genes for phthalate degradation from Burkholderia cepacia DBO1.

Authors:  H K Chang; G J Zylstra
Journal:  J Bacteriol       Date:  1998-12       Impact factor: 3.490

4.  Di(2-ethylhexyl) phthalate inhibits antral follicle growth, induces atresia, and inhibits steroid hormone production in cultured mouse antral follicles.

Authors:  Patrick R Hannon; Katherine E Brannick; Wei Wang; Rupesh K Gupta; Jodi A Flaws
Journal:  Toxicol Appl Pharmacol       Date:  2015-02-18       Impact factor: 4.219

5.  Daily exposure to Di(2-ethylhexyl) phthalate alters estrous cyclicity and accelerates primordial follicle recruitment potentially via dysregulation of the phosphatidylinositol 3-kinase signaling pathway in adult mice.

Authors:  Patrick R Hannon; Jackye Peretz; Jodi A Flaws
Journal:  Biol Reprod       Date:  2014-05-07       Impact factor: 4.285

6.  Di-(2-ethylhexyl)-phthalate as plasticizer in PVC respiratory tubing systems: indications of hazardous effects on pulmonary function in mechanically ventilated, preterm infants.

Authors:  B Roth; P Herkenrath; H J Lehmann; H D Ohles; H J Hömig; G Benz-Bohm; J Kreuder; A Younossi-Hartenstein
Journal:  Eur J Pediatr       Date:  1988-01       Impact factor: 3.183

7.  Exposure to di(2-ethylhexyl) phthalate inhibits luteal function via dysregulation of CD31 and prostaglandin F2alpha in pregnant mice.

Authors:  Meijun Guo; Lidan Lai; Teng Zong; Yan Lin; Bei Yang; Lu Zhang; Mo Li; Haibin Kuang
Journal:  Reprod Biol Endocrinol       Date:  2015-03-03       Impact factor: 5.211

Review 8.  The effects of phthalates on the ovary.

Authors:  Patrick R Hannon; Jodi A Flaws
Journal:  Front Endocrinol (Lausanne)       Date:  2015-02-02       Impact factor: 5.555

9.  Peroxisome proliferator-activated receptors as mediators of phthalate-induced effects in the male and female reproductive tract: epidemiological and experimental evidence.

Authors:  Giuseppe Latini; Egeria Scoditti; Alberto Verrotti; Claudio De Felice; Marika Massaro
Journal:  PPAR Res       Date:  2008       Impact factor: 4.964

Review 10.  Mechanisms of phthalate ester toxicity in the female reproductive system.

Authors:  Tara Lovekamp-Swan; Barbara J Davis
Journal:  Environ Health Perspect       Date:  2003-02       Impact factor: 9.031
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