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Literature DB >> 6751500

Cardiovascular collapse associated with nitrous oxide anaesthetic: a case report.

Abstract

This is a case report of a one year old infant weighing 6.7 kilograms with a preoperative diagnosis of partial anomalous pulmonary venous drainage whose anaesthetic was complicated by cardiovascular collapse following addition of nitrous oxide to oxygen administered to the patient using a T-piece breathing circuit. The cardiovascular pathopharmacology of all the drugs administered to the patient before the event as well as that of nitrous oxide is discussed in detail. The drugs discussed are atropine 0.1 mg (0.01 mg . kg-1), glycopyrrolate 0.07 mg (0.01 mg . kg-1), morphine 0.9 mg (0.14 mg . kg-1) methylprednisone sodium succinate 165 mg (23.5 mg . kg-1) sodium thiopentone 40 mg (5.7 mg . kg-1), metocurine 3.4 mg (0.4 mg . kg-1).

Entities: Chemical Disease Species

Mesh：

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Year: 1982 PMID： 6751500 DOI： 10.1007/bf03009414

Source DB: PubMed Journal: Can Anaesth Soc J ISSN： 0008-2856

16 in total

1. The effect of anaesthesia upon pulmonary circulation.

Authors: G M WYANT; C A CHANG; J E MERRIMAN
Journal: Anesth Analg Date: 1962 May-Jun Impact factor: 5.108

2. The tolerance and safety of intravenously administered benzyl alcohol in methylprednisolone sodium succinate formulations in normal human subjects.

Authors: E Novak; S S Stubbs; E C Sanborn; R M Eustice
Journal: Toxicol Appl Pharmacol Date: 1972-09 Impact factor: 4.219

3. Intravenous methylprednisolone sodium succinate: adverse reactions reported in association with immunosuppresive therapy.

Authors: S S Stubbs; R M Morrell
Journal: Transplant Proc Date: 1973-06 Impact factor: 1.066

Cardiovascular collapse associated with nitrous oxide anaesthetic: a case report.

1. The effect of anaesthesia upon pulmonary circulation.

2. The tolerance and safety of intravenously administered benzyl alcohol in methylprednisolone sodium succinate formulations in normal human subjects.

3. Intravenous methylprednisolone sodium succinate: adverse reactions reported in association with immunosuppresive therapy.

4. Cardiovascular effects of 50 per cent nitrous oxide and 50 per cent oxygen mixture.

5. Left ventricular subendocardial ischemia in severe valvar and supravalvar aortic stenosis. A common mechanism.

6. Effects of a single large intravenous dose of methylprednisolone sodium succinate.

7. Cardiovascular effects of 40 percent nitrous oxide in man.

Review 8. Effects of anesthetics on various organs.

9. Glycopyrrolate compared with atropine in prevention of the oculocardiac reflex during eye-muscle surgery.

10. The autonomic margins of safety of metocurine and d-tubocurarine in the cat.

1. Macro- and microvascular effects of nitrous oxide in the rat.

2. Cardiovascular collapse associated with nitrous oxide administration.

3. Cardiovascular influences of nitrous oxide in spontaneously hypertensive rats.