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Literature DB >> 6749817

DNA replication in a diploid strain of Saccharomyces cerevisiae homozygous for the rad6-1 mutation.

E Haładus, Z Swietlińska, D Zaborowska, J Zuk.

Abstract

The generation time of a diploid strain homozygous for the rad6-1 mutation was 160 min, and the duration of the S phase was 80 min; in the parental heterozygote, these values were 90 and 40 min, respectively. Analysis of DNA sedimentation in an alkaline sucrose gradient revealed that heterozygote high-molecular-weight DNA appeared after 60 min, and homozygote high-molecular weight DNA only after a 100-min pulse.

Entities: Chemical Gene Species

Mesh：

Substances：
DNA, Fungal

Year: 1982 PMID： 6749817 PMCID： PMC221455 DOI： 10.1128/jb.152.1.517-520.1982

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

13 in total

1. Repair of pyrimidine dimers in radiation-sensitive mutants rad3, rad4, rad6 and rad9 of Saccharomyces cerevisiae.

Authors: L Prakash
Journal: Mutat Res Date: 1977-10 Impact factor: 2.433

2. Specificity and frequency of ultraviolet-induced reversion of an iso-1-cytochrome c ochre mutant in radiation-sensitive strains of yeast.

Authors: C W Lawrence; J W Stewart; F Sherman; R Christensen
Journal: J Mol Biol Date: 1974-05-05 Impact factor: 5.469

10. Survival and liquid holding recovery in UV-sensitive strains of Saccharomyces cerevisiae after treatment with chemical mutagens and radiation.

Authors: Z Swietlińska; D Zaborowska; J Zuk
Journal: Acta Microbiol Pol Date: 1976

6 in total

DNA replication in a diploid strain of Saccharomyces cerevisiae homozygous for the rad6-1 mutation.

1. Repair of pyrimidine dimers in radiation-sensitive mutants rad3, rad4, rad6 and rad9 of Saccharomyces cerevisiae.

2. Specificity and frequency of ultraviolet-induced reversion of an iso-1-cytochrome c ochre mutant in radiation-sensitive strains of yeast.

3. The isolation, genetics and survival characteristics of ultraviolet light-sensitive mutants in yeast.

4. The effect of liquid holding on chemical induced lethality and mitotic gene conversion in Saccharomyces cerevisiae.

5. Yeast mutants sensitive to trimethoprim.

6. Estimation of the length of cell cycle phases from asynchronous cultures of Saccharomyces cerevisiae.

7. Lack of chemically induced mutation in repair-deficient mutants of yeast.

8. Effect of reversible inhibition of deoxyribonucleic acid synthesis on the yeast cell cycle.

9. Metabolic suppressors of trimethoprim and ultraviolet light sensitivities of Saccharomyces cerevisiae rad6 mutants.

10. Survival and liquid holding recovery in UV-sensitive strains of Saccharomyces cerevisiae after treatment with chemical mutagens and radiation.

1. Cloning and integrative deletion of the RAD6 gene of Saccharomyces cerevisiae.

2. Induced recombination and reversion of the CDC8 gene in relation to the cell cycle of yeast.

3. Isolation of the RAD18 gene of Saccharomyces cerevisiae and construction of rad18 deletion mutants.

4. Cell cycle parameters in radiation sensitive strains of Saccharomyces cerevisiae.

5. UV-induced mutability in repair-deficient rad6-1 strains of Saccharomyces cerevisiae is caused by a suppressor gene.

Review 6. The RAD6 gene of yeast: a link between DNA repair, chromosome structure and protein degradation?