Literature DB >> 6745393

Changes with hypertension and maturation in the response of stomach fundus to acetylcholine.

C L Seidel, J C Allen, A Mukhopadhyay.   

Abstract

The purpose of these experiments was to compare the contractile response to ACh of stomach fundal strips from hypertensive (SHR) and normotensive (WKY) rats during the development of hypertension. The results indicate that the reactivity to ACh is the same in fundal strips from young SHR and WKY rats; however, with maturation strips from WKY rats undergo a reduction in responsiveness which does not occur in the SHR. Therefore, strips from older SHR rats are more reactive to ACh than are those from age matched WKY rats.

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Year:  1984        PMID： 6745393     DOI： 10.1007/BF01949725

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  Vascular responsiveness to norepinephrine, serotonin, and potassium chloride in veins from spontaneously hypertensive and age-matched Wistar Kyoto rats.

Authors:  M L Cohen; K S Wiley
Journal:  Clin Exp Hypertens       Date:  1979       Impact factor: 1.749

2.  Cumulative dose-response curves. I. Introduction to the technique.

Authors:  J van ROSSUM; F van den BRINK
Journal:  Arch Int Pharmacodyn Ther       Date:  1963-05-01

3.  Evidence for a visceral smooth muscle abnormality in Okamoto spontaneous hypertension.

Authors:  J Altman; F Da Ponte; M Worcel
Journal:  Br J Pharmacol       Date:  1977-04       Impact factor: 8.739

4.  Developmental changes of the contractile activity and the drug sensitivity of smooth muscle of the alimentary tract of guinea pig.

Authors:  H Ohkawa
Journal:  Jpn J Physiol       Date:  1978

5.  Aortic actomyosin content of maturing normal and spontaneously hypertensive rats.

Authors:  C L Seidel
Journal:  Am J Physiol       Date:  1979-07

6.  Age-related changes in vascular responsiveness to cyclic nucleotides and contractile agonists.

Authors:  M L Cohen; B A Berkowitz
Journal:  J Pharmacol Exp Ther       Date:  1974-10       Impact factor: 4.030

7.  The contractility of venous vascular smooth muscle in spontaneously hypertensive or renal hypertensive rats.

Authors:  U Peiper; P Klemt; R Popov
Journal:  Basic Res Cardiol       Date:  1979 Jan-Feb       Impact factor: 17.165

8.  Abnormal biochemistry of subcellular membranes isolated from nonvascular smooth muscles of spontaneously hypertensive rats.

Authors:  C Y Kwan; A K Grover; Y Sakai
Journal:  Blood Vessels       Date:  1982

9.  A sensitive method for the assay of 5-hydroxytryptamine.

Authors:  J R VANE
Journal:  Br J Pharmacol Chemother       Date:  1957-09

10.  Contractility, muscle mass and agonist sensitivity of isolated portal veins from normo- and hypertensive rats.

Authors:  M C Sutter; B Ljung
Journal:  Acta Physiol Scand       Date:  1977-04
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