Literature DB >> 6744730

Beta-tricalcium phosphate delivery system for bone morphogenetic protein.

M R Urist, A Lietze, E Dawson.   

Abstract

An aggregate of biodegradable beta-tricalcium phosphate and bone morphogenetic protein (BMP/TCP) induces the differentiation of cartilage within eight days, cartilage and woven bone within 12 days, and lamellar bone, including bone marrow, within 21 days. The yield of new bone from a 1-mg dose was more than 12 times greater from the TCP/BMP than from the BMP alone. Whether TCP acts as a slow-release delivery system, potentiates the activity of BMP, or serves to distribute BMP in a favorable three-dimensional pattern requires further investigation.

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Year:  1984        PMID: 6744730

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  28 in total

1.  Use of an osteoinductive biomaterial as a bone morphogenetic protein carrier.

Authors:  H Yuan; J D De Bruijn; X Zhang; C A Van Blitterswijk; K De Groot
Journal:  J Mater Sci Mater Med       Date:  2001-09       Impact factor: 3.896

2.  Bone formation induced by calcium phosphate ceramics in soft tissue of dogs: a comparative study between porous alpha-TCP and beta-TCP.

Authors:  H Yuan; J D De Bruijn; Y Li; J Feng; Z Yang; K De Groot; X Zhang
Journal:  J Mater Sci Mater Med       Date:  2001-01       Impact factor: 3.896

3.  Bone morphogenetic protein and ceramic-induced osteogenesis.

Authors:  H Yuan; P Zou; Z Yang; X Zhang; J D De Bruijn; K De Groot
Journal:  J Mater Sci Mater Med       Date:  1998-12       Impact factor: 3.896

Review 4.  The Role of the Microenvironment in Controlling the Fate of Bioprinted Stem Cells.

Authors:  Lauren N West-Livingston; Jihoon Park; Sang Jin Lee; Anthony Atala; James J Yoo
Journal:  Chem Rev       Date:  2020-06-19       Impact factor: 60.622

Review 5.  Biomaterials for Bone Regenerative Engineering.

Authors:  Xiaohua Yu; Xiaoyan Tang; Shalini V Gohil; Cato T Laurencin
Journal:  Adv Healthc Mater       Date:  2015-04-07       Impact factor: 9.933

6.  Enhancement of bone formation with a synthetic matrix containing bone morphogenetic protein-2 by the addition of calcium citrate.

Authors:  Wei Wang; Qingyu Chen; Xiucui Li; Wei Zhang; Lei Peng; Liming Wang; Zhongqin Lin; Huazi Xu; Shifeng Song; Xiaolei Zhang; Shaowen Cheng; Dongquan Kou; Chuanzhu Lv; Ziming Yu
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-03-21       Impact factor: 4.342

7.  Purification and characterization of other distinct bone-inducing factors.

Authors:  E A Wang; V Rosen; P Cordes; R M Hewick; M J Kriz; D P Luxenberg; B S Sibley; J M Wozney
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

8.  Effect of Alendronate with β - TCP Bone Substitute in Surgical Therapy of Periodontal Intra-Osseous Defects: A Randomized Controlled Clinical Trial.

Authors:  Rohini Naineni; Vishali Ravi; Dwijendra Kocherlakota Subbaraya; Jammula Surya Prasanna; Veerendranath Reddy Panthula; Rekha Rani Koduganti
Journal:  J Clin Diagn Res       Date:  2016-08-01

9.  A comparison of the osteoinductive potential of two calcium phosphate ceramics implanted intramuscularly in goats.

Authors:  Huipin Yuan; M Van Den Doel; Shihong Li; C A Van Blitterswijk; K De Groot; J D De Bruijn
Journal:  J Mater Sci Mater Med       Date:  2002-12       Impact factor: 3.896

10.  Enhancement of bone ingrowth in a titanium fiber mesh implant by rhBMP-2 and hyaluronic acid.

Authors:  S Itoh; M Matubara; T Kawauchi; H Nakamura; S Yukitake; S Ichinose; K Shinomiya
Journal:  J Mater Sci Mater Med       Date:  2001-07       Impact factor: 3.896

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