Literature DB >> 6744225

Chromosomes in human large bowel tumors. A study of chromosome #1.

A Reichmann, P Martin, B Levin.   

Abstract

Chromosome studies on 49 patients with large bowel adenocarcinomas showed abnormalities of chromosome #1 in 19 cases (39%). One had monosomy, 13 showed trisomy, and 5 cases had structural abnormalities. Eighteen patients had tumors on the right side of the colon; of these, only 3 had an abnormal #1 (17%); 16 of 28 tumors (57%) located on the left side had abnormalities of #1. The regions of consistent duplication of 1q were q24----q44? The presence or absence of changes of chromosome #1 may be useful as a prognostic indicator in large bowel cancer.

Entities:  

Mesh：

Year:  1984        PMID： 6744225     DOI： 10.1016/0165-4608(84)90062-1

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  8 in total

1.  Karyotype peculiarities of human colorectal adenocarcinomas.

Authors:  L N Konstantinova; E W Fleischman; V I Knisch; A G Perevozchikov; B P Kopnin
Journal:  Hum Genet       Date:  1991-03       Impact factor: 4.132

2.  Numerical aberrations of chromosomes 11 and 17 in colorectal adenocarcinomas.

Authors:  Y Tagawa; T Sawai; T Nakagoe; M Morinaga; T Yasutake; H Ayabe; M Tomita
Journal:  Surg Today       Date:  1996       Impact factor: 2.549

3.  Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.

Authors:  Claire M Payne; Cheray Crowley-Skillicorn; Carol Bernstein; Hana Holubec; Harris Bernstein
Journal:  Clin Exp Gastroenterol       Date:  2011-05-03

4.  Cytogenetic, oncogenetic, and histopathologic characteristics of colorectal carcinomas with 17p abnormalities.

Authors:  D Rau; S Neubauer; A Köster; J Giedl; R Sachse; S Landgraf; A Leipold; T Dingermann; E Gebhart
Journal:  Hum Genet       Date:  1992-04       Impact factor: 4.132

5.  Loss of heterozygosity in hypotriploid cell cultures from testicular tumours.

Authors:  J M Parrington; L F West; S Povey
Journal:  Hum Genet       Date:  1987-11       Impact factor: 4.132

Review 6.  Chromosome 1 in relation to human disease.

Authors:  S Povey; J M Parrington
Journal:  J Med Genet       Date:  1986-04       Impact factor: 6.318

7.  Chromosome 1 in human colorectal tumors. Cytogenetic research on structural changes and their significance.

Authors:  M H Couturier-Turpin; C Esnous; A Louvel; Y Poirier; D Couturier
Journal:  Hum Genet       Date:  1992-02       Impact factor: 4.132

8.  Chromosome 5 allele loss in familial and sporadic colorectal adenomas.

Authors:  M Rees; S E Leigh; J D Delhanty; J R Jass
Journal:  Br J Cancer       Date:  1989-03       Impact factor: 7.640
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.